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Anthocyanins are potent antioxidants that are widely distributed in fruit, vegetables, and red wines. Anthocyanin products are also prescribed as medicines in many countries for treating various di...
Polypharmacy is a general clinical practice, there is a high chance that multiple administered drugs will interfere with each other, such phenomenon is called drug-drug interaction (DDI). DDI occurs w...
Objectives: We investigated pharmacokinetic tissue distributions of Levofloxacin to explain adverse tendon incidents. Methods: The pharmacokinetic profiles of single and multiple dosing of 500 mg Levo...
The pharmacokinetic behavior of amikacin and predictive performance of Sawchuk-Zaske dosing method, have been prospectively evaluated in 31 (16 male, 15 female) critically ill septic patients of mean ...
In this investigation, the pharmacokinetic variables of continuous infusion and intermittent bolus injection of furosemide and the possible relationship between its pharmacokinetic characteristics and...
Background: All contemporary methods of insulin administration are non-physiological. Insulin is not absorbed from the gastrointestinal tract because of its peptide nature. The aim of the present stud...
Background and the purpose of the study: A suitable high-performance liquid chromatography (HPLC) method for determination of celecoxib levels in plasma is of prime need for the pharmacokinetics and b...
Testosterone undecanoate (TU) provides testosterone (T) replacement for hypogonadal men when administered orally but requires multiple doses per day and produces widely variable serum T levels. We i...
Oral administration of 400 mg of testosterone (T) in oil, when combined with the 5 reductase inhibitor dutasteride (D), elevates serum T in medically castrated men to the normal range. In this study...
Population pharmacokinetic data, adjusted for patient characteristics, are recommended for the design of initial dosage regimens of some therapeutically monitored drugs in patients for whom patient-sp...
A sensitive, accurate and rapid reverse phase HPLC method was developed to quantitate plasma levels of metronidazole in order to conduct a comparative bioavailability studies. The drug and internal st...
The learning tools used by this instructor in a pharmacokinetics course offered to entry level PharmD students are presented for the topic of relationship among pharmacokinetic parameters. These tools...
On-line (web-based) pharmacokinetic modules were developed for 25 topics in basic and clinical phar-macokinetics. The modules consist of spreadsheet files, relational databases, and dynamic web. Instr...
Cellular automata are systems composed of two-dimensional cell arrays which change according to specific, pre-determined rules. For this reason, cellular automata were used to illustrate and simulate ...
An internet-based pharmacokinetic teaching module has been developed. This module is interactive, learnercentered, asynchronous, and requires minimal computer knowledge to operate. The main components...

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