搜索结果: 1-11 共查到“医学 thromboxane”相关记录11条 . 查询时间(0.078 秒)
Effects of Gliclazide and Insulin Therapy on Thromboxane B 2 and 6-Keta-PGF 1a Levels in Type II Diabetic Patients
Non insulin dependent diabetes gliclazide thromboxane B2 6-keto-PGF 1a
2009/7/2
Diabetic patients show hemobiological abnormalities such as increased platelet adhesiveness, platelet hyperaggregability, decreased platelet half life, hemorheological abnormalities and altered fibrin...
Dibutyryl cAMP effects on thromboxane and leukotriene production in decompression-induced lung injury
decompression neutrophil lung injury
2009/6/8
Decompression-induced venous bubble formation has been linked to increased neutrophil counts, endothelial cell injury,release of vasoactive eicosanoids, and increased vascular membrane permeability.
Effect of Castration and Androgen Treatment on Sex-Linked Reactivity of Rat Aorta to a Thromboxane-Mimic
castration androgen-treatment vascular reactivity thromboxane-mimic
2009/2/19
In order to examine the possible role of androgens in the isotonic response of the isolated rat aorta, a highly active mimic of thromboxane was employed. The maximum response to this TXA2-mimic U4...
Effects of KP-496, a Novel Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors, on Contractions Induced by Various Agonists in the Guinea Pig Trachea
antagonist anti-asthmatic drugs asthma leukotriene D4 thromboxane A2
2010/11/19
KP-496 produced parallel rightward shifts of the LTD4 and U46619 concentration-response curves in a concentration-dependent manner. Schild plot analyses of the antagonistic activities of KP-496 demons...
Thromboxane A2 mediates cation-induced airway hyperresponsiveness through the bradykinin B2 receptor in guinea pigs
airway hyperresponsiveness bradykinin cationic protein low molecular weight heparin poly-L-lysine 6-keto-PGF1α thromboxane A2
2010/11/26
To elucidate the mechanisms of cationic protein-induced airway hyperresponsiveness (AHR), the airway response to methacholine, and the concentrations of thromboxane B2 (TXB2) and 6-keto-PGF1α in the b...
Effects of olopatadine hydrochloride on the release of thromboxane B2 and histamine from nasal mucosa after antigen-antibody reaction in guinea pigs
allergic rhinitis chemical mediators guinea pigs olopatadine
2010/11/25
Background: Various mediators, such as thromboxane (TX) A2, peptide leukotrienes (P-LT) and histamine, are involved in allergic nasal obstruction. The aim of the present study was to investigate the m...
Sulfidopeptide leukotrienes, but not thromboxane B2 or histamine, are elevated in sputum during exacerbation of asthma
asthma histamine sputum sulfidopeptide leukotrienes thromboxane B2
2010/11/25
Although sulfidopeptide leukotrienes (sLT) are considered to play an important role in the pathogenesis of asthma, their precise action has not been elucidated in asthmatics during exacerbation. In th...
Effect of ramatroban, a thromboxane A2 antagonist, in the treatment of perennial allergic rhinitis
allergic histamine nasal obstruction perennial ramatroban rhinitis thromboxane A2 receptor
2010/11/24
The present study reconfirmed the clinical efficacy of a post-marketed drug, namely ramatroban, in the treatment of allergic rhinitis. In addition, the results suggest that ramatroban suppressed the s...
Additive effect of cysteinyl leukotriene or thromboxane modifiers to inhaled corticosteroids in asthmatic patients
asthma corticosteroid cysteinyl leukotriene thromboxane
2010/11/22
Bronchial asthma is a chronic inflammatory disease of the conducting airways. Current asthma treatment guidelines recommend inhaled corticosteroids (ICS) as the first-line maintenance therapy for mild...
Urinary leukotriene E4 and 11-dehydro-thromboxane B2 excretion in children with bronchial asthma
bronchial asthma cysteinyl leukotrienes 11-dehydro-thromboxane B2 leukotriene E4 thromboxane A2
2010/11/22
Urinary LTE4 levels during an acute attack (median 476 pg/mg creatinine; range 191-1100 pg/mg creatinine) and during the stable condition (median 332 pg/mg creatinine; range 128-965 pg/mg creatinine) ...
Effect of a thromboxane A2 receptor antagonist, ramatroban (BAY u 3405), on inflammatory cells, chemical mediators and non-specific nasal hyperreactivity after allergen challenge in patients with perennial allergic rhinitis
eosinophil nasal allergen challenge nasal mucosal reactivity perennial allergic rhinitis ramatroban thromboxane A2 receptor antagonist
2010/11/29
In some clinical studies performed in patients with perennial allergic rhinitis, ramatroban, a new thromboxane A2 receptor antagonist, significantly improved nasal symptoms. As yet the mechanism of ac...