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Effects of Theophylline on Chronic Inflammatory Lung Injury Induced by LPS Exposure in Guinea Pigs
airway hyperreactivity COPD goblet cell hyperplasia lipopolysaccharide exposure theophylline
2010/11/18
Repetitive exposure to LPS induced an influx of inflammatory cells into the BALF. Histological changes such as accumulation of inflammatory cells in the lung parenchyma, enlargement of alveoli, swelli...
A Prospective Survey on Safety of Sustained-Release Theophylline in Treatment of Asthma and COPD
adverse drug reactions asthma COPD safety evaluation sustained-release theophylline
2010/11/19
3,921 patients were included in the safety evaluation. No serious adverse reactions were observed among the patients in this survey, although 54 patients (1.38%) exhibited non-serious adverse reaction...
A Randomized Open-Label Comparative Study of Montelukast versus Theophylline Added to Inhaled Corticosteroid in Asthmatic Children
childhood asthma inhaled corticosteroid montelukast peak expiratory flow sustained-release theophylline
2010/11/19
A significant increase in morning PEF was observed in the add-on montelukast group as compared with the add-on theophylline group at Week 2 (change from baseline of 22.8 L/minvs. 8.7 L/min; p = 0.041 ...