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Stimulation of the proliferation and differentiation of Leydig cell precursors after the destruction of existing Leydig cells with ethane dimethyl sulphonate（EDS）can take place in the absence of LH
proliferation differentiation Leydig cell precursors
2009/2/23
In hypophysectomized rats, 2 days after the administration of the cytotoxic drug ethane dimethyl sulphonate (EDS), the proliferative activity of Leydig cell precursors increased six-fold. Thus, fact...
Transferrin secretion in response to different modes of FSH stimulation and cycloheximide in superfused Sertoli cell cultures
Transferrin secretion FSH stimulation cycloheximide superfused Sertoli cell cultures
2009/2/23
The influence of different modes of FSH stimulation and cycloheximide on transferrin secretion by rat Sertoli cells was investigated using a superfusion culture system. Sertoli cells from 18-day-old...
Stimulation of sperm production by human chorionic gonadotropin after prolonged gonadotropin suppression in normal men
sperm production human chorionic gonadotropin prolonged gonadotropin suppression normal men
2009/2/20
The precise hormonal milieu required for quantitatively normal spermatogenesis in man is unclear. The authors previously have shown that both supraphysiologic dosages of human chorionic gonadotropin...
Response to acute hCG stimulation and steroidogenic potential of Leydig cell fibroblastic precursors in humans
acute hCG stimulation steroidogenic potential Leydig cell fibroblastic precursors humans
2009/2/20
The process of early testosterone (T) secretion and Leydig cell differentiation in humans was studied to explore the steroidogenic capacity of Leydig cell fibroblastic precursors. Seven cryptorchi...
Catecholamine Stimulation of Androgen Production by Mouse Interstitial Cells in Primary Culture
catecholamines Leydig cells androgens cell culture
2009/2/19
The catecholamines isoproterenol, epinephrine, and norepinephrine stimulated androgen production by mouse interstitial cells in primary culture. The amount of androgen produced in response to maximu...
In Vitro Gonadotropin Stimulation of Bovine Sertoli Cell Ornithine Decarboxylase Activity
ornithine decarboxylase Sertoli cell gonadotropins bovine calf
2009/2/19
The activity of ornithine decarboxylase (ODC) was determined in primary cultures of bovine Sertoli cells after gonadotropin stimulation in vitro. A significant increase in both ODC activity and putr...
FSH Stimulation of cAMP Accumulation in Hamster Sertoli Cells：Effect of Age and Optic Enucleation
cAMP Sertoli cells hamsters optic enucleation
2009/2/19
Sertoli cells isolated from immature, adult, and adult optic-enucleated hamsters respond to FSH, but not to LH, with an increase in cAMP accumulation. There is an age-related decline in responsivene...
The Aging Leydig Cell: III. Gonadotropin Stimulation in Men
human aging Leydig cells testosterone 17OH-progesterone estradiol human chorionic gonadotropin
2009/2/19
To assess the capacity of aging human Leydig cells to respond to intramuscular injection of hCG, six healthy men, 68 to 86 years old, and eight healthy younger subjects, 25 to 42 years old, were s...
Prolactin Stimulation of Testicular Steroid Biosynthesis in the Male Rat
prolactin LHRH 17-hydroxylase desensitization steroidogenesis LH receptor prolactin receptor
2009/2/19
The effect of prolactin on testicular steroidogenesis was studied in intact adult male rats and in animals treated for 12 days with the LHRH-agonist [D-Ala6, des-Gly-NH210]LHRH ethylamide (LHRH-agon...
Glycosaminoglycan Stimulation of the In Vitro Conversion of Boar Proacrosin into Acrosin
acrosomal enzymes acrosome reaction proacrosin acrosin glycosaminoglycan
2009/2/18
Glycosaminoglycans obtained from shark cartilage, whale cartilage, porcine intestinal mucosa, porcine skin, and human umbilical cord were found to accelerate the in vitro conversion of highly puri...
Follicle-stimulating hormone and testosterone stimulation of immature and mature Sertoli cells in vitro：inhibin and N-cadherin levels and round spermatid binding
Follicle-stimulating hormone testosterone stimulation immature mature Sertoli cells
2009/2/18
The in vitro response of Sertoli cells isolated from adult rat testes to testosterone (T) and follicle-stimulating hormone (FSH) treatment was investigated. Sertoli cells from >70-day-old Sprague-...
Does age-associated reduced Leydig cell testosterone production in Brown Norway rats result from under-stimulation by luteinizing hormone?
Aging testis steroids rat
2009/2/18
Previous studies have shown that reductions in Leydig cell testosterone production occur with aging in the Brown Norway rat. The recent observation that changes in luteinizing hormone (LH) pulse i...
A new method to generate canine seminal emission and its application to men：direct electrical stimulation of the vas deferens
generate canine seminal emission direct electrical stimulation vas deferens
2009/2/12
Seminal emission from the ejaculatory duct (SEED) by direct electrical stimulation of the vas deferens was investigated in the dog, and the technique was applied to men. The stimulus parameters used w...
Stimulation of cryopreserved epididymal spermatozoa of the domestic cat using the motility stimulants caffeine, pentoxifylline, and 2'-deoxyadenosine
Domestic cat motility stimulants hyperactivation
2009/2/12
We have investigated the effects of caffeine, pentoxifylline, and 2'-deoxyadenosine on the motion characteristics and longevity of domestic cat spermatozoa. Freshly collected or cryopreserved dome...
The application of pentoxifylline in the stimulation of sperm motion in men undergoing electroejaculation
Spinal cord injury electroejaculation sperm
2009/2/7
The ability of pentoxifylline to stimulate the motion characteristics of antegrade and retrograde sperm collected at the time of electroejaculation with a rectal probe was assessed in six neurologic...