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Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
DNA methylation genomic DNA folate homocysteine humans elderly women
2016/6/8
Background: Methylation of genomic DNA is dependent on an
adequate supply of folate coenzymes. Previous data support the
hypothesis that abnormal DNA methylation plays an integral
role in carcinoge...
Folate, DNA methylation, and gene expression: factors of nature and nurture
nature and nurture nature and nurture
2016/6/8
Folate provides the one-carbon units required for purine and
thymidylate syntheses and for methylation of a wide variety of
essential biological substances, including phospholipids, proteins,
DNA, ...