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Narcotic potency of N2, A, and N2O evaluated by the physical performance of mouse colonies at simulated depths
animal mice narcosis nitrogen argon nitrous oxide
2009/7/20
The physical performance of colonies of deer mice was studied in various inert gas environments at pressures up to 31 ATA. The mice were housed in habitats wherein their diurnal running activity and s...
Rate of pressure change and hyperbaric bradycardia in the mouse sinus node
cardiac animal mice sinus node
2009/7/17
Sinus node preparations from mice were hydraulically compressed at 10, 100, and 500 atm x min-1 in Tyrode's solution at 27 degrees C. At the highest compression rate, both a delay and a more pronounce...
Influence of nitrous oxide, nitrogen, neon, and helium on the beating frequency of the mouse sinus node at high pressure
cardiac animal mice nitrous oxide nitrogen neon helium sinus node
2009/7/17
The beating frequency (BF) reducing effect of 150 atm of hydrostatic pressure on mammalian cardiac pacemaker tissue (hyperbaric bradycardia) was counteracted by dissolved gas only if the gas was added...
Alterations in mouse fecal flora associated with hyperbaric stress
animal mice fecal microflora hyperbaric heliox
2009/7/16
The effect of hyperbaric stress on the composition of fecal microflora was investigated in the mouse. Mice were exposed to 35 ATA with normoxic PO2 concentration in a helium atmosphere at 35 degrees C...
Effect of pressure on oxidative metabolism of drugs by mouse hepatic microsomes
animal mice oxidative metabolism hepatic microsomes delta-9-tetrahydrocannabinol Cannabis drug
2009/7/14
The metabolism of antipyrene and delta-9-tetrahydrocannabinol (delta-9-THC) was studied in vitro with mouse liver supernatant and 105,000 g microsomes at 450 atm pressure. No significant change in rat...
Effect of oxygen on phagocytic and adherence functions in mouse spleen macrophages
hyperoxia wound healing phagocytosis cell adherence cell culture animal mouse
2009/5/8
The effects of varied of varied oxygen partial pressures were tested on the phagocytic and adherence functions of mouse spleen macrophages. The evaluation was accomplished in vitro using standard cyt...