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2023年11月9日，皖南医学院基础医学院与深圳大学共建实验平台研究人员孟媛与深圳大学刘宝华团队共同在《Nature》子刊《Nature Aging》（IF=16.6）在线发表题为“CD133+ endothelial-like stem cells restoreneovascularization and promote longevity in progeroid and naturally...
随着年龄的增长，肌肉质量和力量逐渐减少，称为肌肉减少症，导致老年人日常活动能力有限，影响生活质量和健康寿命。虽然导致这种病理的机制尚未完全明确，但活性氧、神经肌肉接头(NMJ)中断和神经丢失是重要的危险因素。
When new mothers complain that all those sleepless nights caring for their newborns are taking years off their life, they just might be right. A year after giving birth, the 'biological age' of mother...
2019年3月7日，广东医科大学衰老研究所刘新光课题组在衰老权威杂志Aging Cell (JCR I区，IF 7.627),在线发表题为“The p53/miRNAs/Ccna2 pathway serves as a novel regulator ofcellular senescence: Complement of the canonical p53/p21 pathway”的研究论文，...
An Anti-Aging Protein Could Be Targeted to Rejuvenate Immune Cells
Anti-Aging Protein Rejuvenate Immune Cells
2017/12/19
Anti-aging proteins have long been shown to protect against age-related diseases, such as cancer, neurodegeneration, and cardiovascular disease. A study by researchers at the Gladstone Institutes now ...
Artificial Blood Vessels Mimic Rare Accelerated Aging Disease（图）
Artificial Blood Vessels Mimic Accelerated Aging Disease
2017/9/5
Biomedical engineers have grown miniature human blood vessels that exhibit many of the symptoms and drug reactions associated with Hutchinson-Gilford Progeria Syndrome—an extremely rare genetic diseas...
Aerobic Exercise Training Improves Orthostatic Tolerance in Aging Humans
CAROTID ARTERIAL BAROREFLEX PEAK O2 UPTAKE LOWER-BODY NEGATIVE PRESSURE CEREBRAL TISSUE OXYGENATION PRESYNCOPE
2018/4/24
Purpose This study was designed to test the hypothesis that aerobic exercise training of the elderly will increase aerobic fitness without compromising orthostatic tolerance (OT).
Methods Eight healt...
Workshop on Aging Well with Technology for Maintaining Good Mental and Cognitive Health
Maintaining Good Mental Cognitive Health
2017/3/31
Many countries are becoming aging societies and the proportion of people over the age of 65 is growing worldwide. There is a growing realization that the way we deal with the aging population has to c...
2017老化和老化相关疾病的机制 Keystone Symposia（2017 Keystone Symposia on Aging and Mechanisms of Aging-Related Disease）
Aging-Related Disease protein homeostasis
2017/3/7
Populations are aging rapidly worldwide, particularly in Asia, driving a strong interest in aging/longevity research. This Keystone Symposia meeting will capture the cutting-edge front of this excitin...
Effects of aging and freezing/thawing sequence on quality attributes of bovine Mm. gluteus medius and biceps femoris
Aging Freezing Glutathione Peroxidase Purge Thawing
2017/3/9
The effects of aging and freezing/thawing sequence on color, physicochemical, and enzymatic characteristics of two beef muscles (Mm. gluteus medius, GM and biceps femoris, BF) were evaluated.
Fat Replacement of Paraspinal Muscles with Aging in Healthy Adults
MRI MUSCLE FAT REPLACEMENT PARASPINAL MUSCLE AGING
2018/4/24
Purpose The aims of this study were to investigate the age-related changes in fatty replacement and cross-sectional area (CSA) of cervical, thoracic, and lumbar paraspinal muscles versus leg muscles i...
Aging, body composition, and lifestyle: the Fels Longitudinal Study
Body composition aging physical activity
2016/6/1
Changes in body composition in men and women
occur with age, but these changes are affected by numerous
covariate factors.
There is an inevitable increase in the older adult population nowadays due to the dropping birth rates and longer life expectancy (World Health Report, 2010). The rates of the aging population are gro...
Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium
DNA methylation epidemiology fatty acids genetic variants plasma lipids
2018/11/28
Background: DNA methylation is influenced by diet and single nucleotide polymorphisms (SNPs), and methylation modulates gene expression.
Factors Influencing the Successful Aging of Iranian Old Adult Women
Aging Female Qualitative Research Iran
2015/11/9
Background: Aging is an irreversible natural process characterized by a decline in both the physical and mental status of individuals. Because of multiple factors, this process and its consequences va...