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Currently there is considerable interest in the potential health benefits of oil seeds, such as soy and flaxseed, especially in relation to cardiovascular disease and cancer.
To better understand the effect of androgen on the growth and function of accessory sex glands, it can be useful to determine the presence or absence of the androgen receptor (AR) in the individual ce...
The androgen signalling axis is critical for the development and progression of prostate cancer. Therefore, the mainstay treatments for metastatic disease are hormonal manipulations aimed at reducing ...
Elderly men have a relative deficiency of testosterone compared with younger men (i.e., partial androgen deficiency of the aged male (PADAM)). In the cognitive impairment in elderly men, testosterone ...
The aim of the present study was to investigate the androgen receptor (AR) distribution in epididymal cells of developing rats and the effects of prepubertal epididymal obstruction upon AR distributio...
Exercise is being increasingly established as a key adjuvant therapy in clinical oncology. As research has demonstrated the beneficial effect of exercise for cancer management, a growing number of pat...
The biological activities of androgen are largely mediated via androgen receptor (AR). Although a partial sequence AR cDNA was revealed in canaries and zebra finch, AR cDNA has not been cloned in quai...
Endocrine disrupting chemicals (EDCs) are compounds that alter the production, secretion, action, and elimination of endogenous hormones. In the environment, organisms are exposed to many different ty...
Japanese quail (Coturnix coturnix japonica) is widely used in avian reproduction tests and avian sex reversal screening tests for evaluating adverse effects of endocrine disrupting chemicals (EDCs). H...
Bone sialoprotein (BSP) is a phosphorylated and sulfated noncollagenous protein that has been shown to have the ability to mediate cell attachment through an Arg-Gly-Asp (RGD) sequence and to bind hy...
ABP, a Sertoli cell secretory product, was identified in the seasonal rodent Octodon degus (Molina, 1872). It was shown to be present in cytosols from the testis and epididymis. It migrated with a...
To determine the hormonal effects of MK-906, an orally active 5 alpha-reductase inhibitor, on serum androgens and androgen conjugates, 12 healthy men were given 10, 20, 50, and 100 mg MK-906 2 weeks a...
In this study, changes in the number of androgen binding sites that occur in cytosols of epididymis, vas deferens and seminal vesicle of mice from 10 to 90 days of age are described. Specific satura...
The influence of germ cells (greater than 85% pachytene spermatocytes) on vectorial secretion of androgen binding protein (ABP) and transferrin by immature rat Sertoli cells was investigated using t...
Tritiated androgen receptor complex was partially purified by ammonium sulfate precipitation at 15 to 37% saturation from rat testicular or prostatic cytosols. A greater amount of prostatic tritiate...

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