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Background: Plasma apolipoprotein (apo) E, a sialoprotein, plays an important role in reverse cholesterol transport. Previously, we showed that chronic alcohol consumption impairs glycosylation of ...
Background: In general populations, the effects of dietary cholesterol on blood cholesterol concentrations are modest. However, the relation is stronger in those with an ɛ4 allele in the apolipop...
Apolipoprotein B (apoB) containing lipoproteins are major lipoproteins in blood and the elevated concentration in plasma may lead to increased transport of lipoproteins into adipose tissues resulting ...
To explore the possible endocrine-disrupting effect of cadmium (Cd), we have tested its role on very-low-density apolipoprotein II mRNA (apoVLDL II) expression by diethylstilbestrol (DES) in Japanese ...
Various relations between apolipoprotein E (apo E) and diabetic nephropathy have been reported. In this study, the question of whether there is any relation between apo E genotypes and microalbuminuri...
The aim of the study was to establish apolipoprotein E genotype in the patients with coronary heart disease (CHD) who are inhabitants of the north-east of Turkey. The study involved 106 patients (70 m...
Lipoprotein oxidation may play a pivotal role in the pathogenesis of atherosclerosis, and vitamin E and b-carotene have been proposed to prevent the development and progression of atherosclerosis. Th...
TNF-α is present in atherosclerotic lesions, activates endothelial adhesion molecule expression, stimulates the release of proinflammatory cytokines and matrix metalloproteinases and promotes smooth ...
Apolipoprotein E (apo E) is an important constituent of plasma lipoproteins and is believed to be involved in the regulation of lipid transport and distribution between tissues. The production of ...
Background: Low-fat, high-carbohydrate (LFHC) diets have been shown to increase plasma concentrations of lipoprotein(a) [Lp(a)] and of triacylglycerol- rich lipoproteins (TRLs).Objective: We tested wh...
Background: Plasma lipoproteins may be classified by their apolipoprotein composition. The lipoprotein subclass containing apolipoproteins B and C (LpB:C) is considered the most atherogenic.Objective:...
阿朴脂蛋白A-IV(apoA-IV)作为一种载脂蛋白,是调节血浆脂蛋白代谢家族中最大的成员。在哺乳动物中,apoA-IV主要是由小肠绒毛上皮细胞在脂肪吸收时合成,然后通过刚合成的乳糜微粒表面进入循环。apoA-IV在人类和啮齿类动物肠道中广泛存在,主要由小肠和肝脏分泌,其合成和分泌受乳糜微粒合成、PYY、Leptin等多种因素的影响。并且其生理作用众多,除了调节小肠脂肪的吸收和乳糜微粒的组装,对动...
摘要研究载脂蛋白E (ApoE) 基因多态性与中国东北汉族2型糖尿病合并脑梗死的关系。采用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)技术,检测了208例个体的ApoE基因多态性,其中对照(CON)组69例,2型糖尿病无大血管病变(T2DM)组67例和2型糖尿病合并脑梗死(T2DMCI)组72例;同时测定了其中70例T2DMCI患者的血脂含量。CON组等位基因频率为:ε2 9.6%、ε3...

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