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Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential as new therapeutic agents to inhibit cancer-cell growth. However, delivering these sma...
Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential as new therapeutic agents to inhibit cancer-cell growth. However, delivering these sma...
Background:: Little is known about the duration of combination therapy for patients with chronic hepatitis B (CHB) and suboptimal response to nucleos(t)ide analogues(NAs) monotherapy.
Nucleos(t)ide analogues, active against hepatitis B polymerase, suppress viral replication and improve clinical outcome. However, the emergence of drug-resistant mutants can result in treatment failur...
People with bipolar disorder are less likely to suffer a relapse if they are taking both lithium and sodium valproate rather than the drug valproate alone, an Oxford University study has shown.Sodium ...
Background: Ovarian cancer is the leading cause of death among all gynecologic cancers in developed countries. The standard treatment for advanced ovarian cancer consists of cytoreductive surgery asso...
Background: In order to prevent tumor metastasis, we investigated more effective inhibition by combination therapy. The competition with native adhesion molecules by cell-binding domain, inhibition of...
A number of anticonvulsant drugs such as phenytoin, phenobarbital and primidone cause disturbances in bone mineral metabolism (1,2). Side effects of carbamazepine (CBZ) seem to be fewer than with othe...
The objective of our study was to assess the effectiveness of combining medicated urethral system for erection (MUSE) with sildenafil citrate in men unsatisfied with the sildenafil alone. Baseline a...
Hydatid disease is the most common helminthic disease in human beings; however, spinal hydatid cyst accounts for 1% of all cases. We report a case of spinal hydatid disease that relapsed after surgery...
The main ingredient of grape seed proanthocyanidin extract (GSPE), is proanthocyanidin, a kind of flavonoid. Proanthocyanidins are known to have a variety of biological regulatory activities, such as ...
Background: Combination of suplatast tosilate with tacrolimus ointment was reported to reduce the dose of tacrolimus ointment with maintained treatment efficacy for refractory facial erythema in atopi...

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