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The n−3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans
Systemic arterial compliance n− 3 fatty y acids plasma lipids arterial pressure cardiovascular disease eicosapentaenoic acid docosahexaenoic acid
2016/12/19
Background: n−3 Fatty acids influence vascular function, but the effect of individual fatty acids on systemic arterial compliance (SAC) has not been reported. SAC, which reflects arterial e...
A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study
DHA EPA inflammation men and women randomized controlled trial risk factors
2018/12/13
Background: To date, most studies on the anti-inflammatory effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in humans have used a mixture of the 2 fatty acids in various forms and...
Effects of Short-Term Docosahexaenoic Acid Supplementation on Markers of Inflammation after Eccentric Strength Exercise in Women
Delayed-onset muscle soreness omega-3 fatty acids fish oil
2016/3/11
The omega-3 fatty acid docosahexaenoic acid (DHA) has anti-inflammatory and anti-nociceptive (pain inhibiting) effects. Because strenuous exercise often results in local inflammation and pain, we hypo...
Rapamycin Inhibits Expression of Elongation of Very-long-chain Fatty Acids 1 and Synthesis of Docosahexaenoic Acid in Bovine Mammary Epithelial Cells
Bovine Mammary Epithelial Cells Mammalian Target of Rapamycin Complex
2016/11/10
Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth and metabolism and is sufficient to induce specific metabolic processes, including de novo lipid biosynthesis. El...
Comparison of the Effects of Eicosapentaenoic Acid With Docosahexaenoic Acid on the Level of Serum Lipoproteins in Helicobacter pylori:A Randomized Clinical Trial
Helicobacter pylori Eicosapentaenoic Acid Docosahexaenoic Acid Cholesterol Triglyceride
2015/10/16
Background: Helicobacter pylori infection is the most common chronic bacterial infection around the world and an important cause of gastrointestinal disorders, which might be involved in the pathogene...
A Dietary Supplement with a High Eicosapentaenoic Acid to Docosahexaenoic Acid Ratio Reduces Triglyceride Levels in Mildly Hypertriglyceridemic Subjects
Omega-3 Fatty Acids Dietary Supplements Lipid Lowering Medications
2013/1/29
There is compelling evidence that omega-3 long-chain polyunsaturated fatty acids (n-3 PUFA), eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) provide cardioprotective benef...
Arachidonic acid–and docosahexaenoic acid–enriched formulas modulate antigen-specific T cell responses to influenza virus in neonatal piglets
Arachidonic acid docosahexaenoic acid immunity growth piglets
2008/12/12
Background: Whereas the immunomodulatory effects of feeding either arachidonic acid (AA) or docosahexaenoic acid (DHA) separately have been previously investigated, little is known about the immunomod...
Maternal consumption of a docosahexaenoic acid–containing functional food during pregnancy: benefit for infant performance on problem-solving but not on recognition memory tasks at age 9 mo1,2,3
Docosahexaenoic acid DHA pregnancy infants cognition problem solving recognition memory
2008/12/12
Background: There are few studies reporting on docosahexaenoic acid (DHA, 22:6n–3) supplementation during pregnancy and infant cognitive function. DHA supplementation in pregnancy and infant problem s...
The importance of fish and docosahexaenoic acid in Alzheimer disease1,2
fish docosahexaenoic acid Alzheimer disease
2008/12/9
Reprints not available. Address correspondence to WE Connor, Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Medicine, L465, Oregon Health & Science University, Portland, OR ...
Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
colonic epithelial cells Low dose docosahexaenoic acid
2008/4/23
The nucleoside analogue arabinosylcytosine (araC) has been used for many years in the treatment of acute leukemia. Evidence in the literature suggests that araC may inhibit the growth of human colon c...
Effects of docosahexaenoic acid–rich n−3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study
PBMCs EPA
2016/12/30
Dietary fish or fish oil rich in n−3 fatty acids (n−3 FAs), eg, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), ameliorate inflammatory reactions by various mechanisms. Whereas...
Supplementing lactating women with flaxseed oil does not increase docosahexaenoic acid in their milk
Fatty acids breast milk human milk
2016/12/28
Flaxseed oil is a rich source of 18:3n−3 (α-linolenic acid, or ALA), which is ultimately converted to 22:6n−3 (docosahexaenoic acid, or DHA), a fatty acid important for the development of ...
Incorporation of docosahexaenoic acid into nerve membrane phospholipids: bridging the gap between animals and cultured cells
phosphatidylcholine brain retina
2017/1/4
Functional maturation of nervous tissues depends on membrane accretion of docosahexaenoic acid (DHA). Animal studies have shown that incorporation of dietary DHA into membrane phospholipids is dose de...
Higher maternal plasma docosahexaenoic acid during pregnancy is associated with more mature neonatal sleep-state patterning
Long-chain polyunsaturated fatty acids long-chain PUFAs docosahexaenoic acid central nervous system infant sleep sleep recordings active sleep quiet sleep pregnancy prenatal nutrition maternal diet phospholipids
2016/12/19
Background: The effect of docosahexaenoic acid (DHA) on the developing fetal central nervous system (CNS) and related functional outcomes in infancy remain unexplored. Sleep and wake states of ne...
A randomized trial of supplementation with docosahexaenoic acid–rich tuna oil and its effects on the human milk cytokines interleukin 1β, interleukin 6, and tumor necrosis factor α
Docosahexaenoic acid human milk cytokines n− 3 fatty acids human milk cells interleukin 1β interleukin 6 tumor necrosis factor
2016/12/17
Background: Increased consumption of n−3 long-chain polyunsaturated fatty acids (PUFAs) has been recommended during pregnancy and lactation. The production of proinflammatory cytokines by h...