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重庆大学医学院王亚洲教授课题组基于神经节苷脂Monosialotetrahexosylganglioside(GM1)胶束跨越血脑屏障(Blood-brain barrier,BBB)的能力,结合PTN-PTPRZ1信号轴介导M2型肿瘤相关巨噬细胞(M2 TAMs)与胶质母细胞瘤干细胞(GSC)在肿瘤免疫抑制微环境(Tumor microenvironment,TME)形成中的重要作用,构建了M2...
山西医科大学口腔医学院卓越口腔医生创新班学生郝雨佳在Journal of Controlled Release发文阐明EVs的生物发生机制(图)
山西医科大学 口腔医学 细胞外囊泡
2023/12/25
近日,口腔疾病防治与新材料山西省重点实验室口腔干细胞科研团队在国际知名期刊Journal of Controlled Release(中科院分区Top 1区,IF=9.776) 发表了题为“Promotion or inhibition of extracellular vesicle release: emerging therapeutic opportunities”的综述。论文第一作者为山...
中南大学湘雅药学院丁劲松-周文虎教授团队在《Journal of Controlled Release》杂志发表中西药结合研究成果(图)
周文虎教授 湘雅药学院 中西药结合 伊马替尼
2023/3/27
近期,中南大学湘雅药学院丁劲松-周文虎教授团队与湖南中医药大学第一附属医院邓桂明研究员团队教授合作,在药剂学领域权威期刊《Journal of Controlled Release》(IF=9.776)上发表了题为“Imatinib Co-Loaded Targeted Realgar Nanocrystal for Synergistic Therapy of Chronic Myeloid L...
Simple new testing method aims to improve time-release drugs(图)
new testing method aims improve time-release drugs
2020/12/11
When you take a time-release drug, you count on it doing what the package says: release the drug slowly into your bloodstream to provide benefits over the specified period of time. When the drug disso...
苏州大学材料化学化工学部钟志远教授应邀担任药剂学顶级期刊Journal of Controlled Release副主编(图)
苏州大学材料化学化工学部 钟志远 教授 药剂学 顶级期刊
2019/7/22
近日,我校材料化学化工学部钟志远教授应Elsevier出版社和美国普渡大学教授Kinam Park主编的邀请,担任Journal of Controlled Release(JCR)亚洲区副主编。JCR是国际控制释放学会(Controlled Release Society)的官方杂志,影响因子7.901,是国际药剂学领域排名第一的专业期刊。钟志远教授研究领域涉及生物医用高分子材料、药物控制释放及...
Effect of Melatonin from Slow-Release Implants on Aquaporins (AQP1 and AQP4) in the Ovine Choroid Plexus
AQPs brain location mimicked short days cerebrospinal fluid photoperiod ewe
2018/3/5
Aquaporins (AQPs) play important role in the cerebrospinal fluid (CSF) secretion and AQP1 and AQP4 are
localized in the choroid plexus (CP), which is the main place of CSF production. In ewes, season...
Researchers Program Biomaterials With ‘Logic Gates’ That Release Therapeutics In Response To Environmental Triggers(图)
Researchers Program Biomaterials Logic Gates Release Therapeutics Environmental Triggers
2018/2/1
Drug treatments can save lives, but sometimes they also carry unintended costs. After all, the same therapeutics that target pathogens and tumors can also harm healthy cells.To reduce this collateral ...
Influence of polymer-coated slow-release urea on total tract apparent digestibility, ruminal fermentation and performance of Nellore steers
Slow-release Urea Ammonia Average Daily Gain Non-protein Nitrogen
2017/3/7
Two experiments were performed to evaluate the effects of coated slow-release urea on nutrient digestion, ruminal fermentation, nitrogen utilization, blood glucose and urea concentration (Exp 1), and ...
Capsaicin-induced satiety is associated with gastrointestinal distress but not with the release of satiety hormones,
capsaicin gastrointestinal distress gastrointestinal peptides satiety CCK GLP-1 gallbladder
2018/11/27
Background: Capsaicin, which is the major pungent principle in chili peppers, is able to induce satiety and reduce caloric intake. The exact mechanism behind this satiating effect is still unknown. We...
Effects of β-Glucan on the Release of Nitric Oxide by Macrophages Stimulated with Lipopolysaccharide
β-Glucan Lipopolysaccharide [LPS] Nitric Oxide [NO] RAW 264.7 Cells STAT1
2016/11/10
This research analyzed the effect of β-glucan that is expected to alleviate the production of the inflammatory mediator in macrophagocytes, which are processed by the lipopolysaccharide (LPS) of Esche...
Effects of Combining Feed Grade Urea and a Slow-release Urea Product on Performance, Dietary Energetics and Carcass Characteristics of Feedlot Lambs Fed Finishing Diets with Different Starch to Acid Detergent Fiber Ratios
Slow-release Urea Finishing Lambs Growth Performance Dietary Energetics Carcass
2016/12/28
Recent findings have shown that microbial nitrogen flow and digestible energy of diets are increased when urea is combined with a slow-release urea (SRU) in diets with a starch to acid detergent fibre...
Effects of Time-Release Caffeine Containing Supplement on Metabolic Rate, Glycerol Concentration and Performance
Caffeine bioavailability energy multiple object tracking
2015/8/28
This study compared caffeine pharmacokinetics, glycerol concentrations, metabolic rate, and performance measures following
ingestion of a time-release caffeine containing supplement (TRCAF) versus a...
Effects of 28-days ingestion of a slow-release energy supplement versus placebo on hematological and cardiovascular measures of health
Energy supplement Slow-release Caffeine Health Safety Comprehensive blood chemistry Lipid profile Complete blood counts Resting heart rate Blood pressure
2015/7/29
Recently, slow release tablets have been developed to prolong energy release throughout the day. The efficacy of the delivery of slow-release caffeine alone is fairly well documented; however, an asse...
Research article Vernonia cinerea Less. supplementation and strenuous exercise reduce smoking rate: relation to oxidative stress status and beta-endorphin release in active smokers
Vernonia cinerea Less supplementation and strenuous exercise
2015/7/20
Volunteer smokers were randomly divided into four groups: group 1: VC supplement; group 2: exercise with
VC supplement; group 3: exercise; and group 4: control. VC was prepared by wash and dry techn...
Serotonin, GnRH-A, and dopamine interaction in the control of in vivo luteinizing hormone release in Prussian carp (Carassius gibelio Bloch) at the time of gonad recrudescence
gonadotropin-releasing hormone analoque LH
2015/7/7
The effects of serotonin (5-HT), GnRH analogue (D-Ala6
LHRH, GnRH-A) and dopamine
antagonist – pimozide (PIM), on luteinizing hormone (LH) release in mature Prussian carp female (Carassius
gibel...