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重庆大学医学院王亚洲教授课题组基于神经节苷脂Monosialotetrahexosylganglioside(GM1)胶束跨越血脑屏障(Blood-brain barrier,BBB)的能力,结合PTN-PTPRZ1信号轴介导M2型肿瘤相关巨噬细胞(M2 TAMs)与胶质母细胞瘤干细胞(GSC)在肿瘤免疫抑制微环境(Tumor microenvironment,TME)形成中的重要作用,构建了M2...
近日,口腔疾病防治与新材料山西省重点实验室口腔干细胞科研团队在国际知名期刊Journal of Controlled Release(中科院分区Top 1区,IF=9.776) 发表了题为“Promotion or inhibition of extracellular vesicle release: emerging therapeutic opportunities”的综述。论文第一作者为山...
近期,中南大学湘雅药学院丁劲松-周文虎教授团队与湖南中医药大学第一附属医院邓桂明研究员团队教授合作,在药剂学领域权威期刊《Journal of Controlled Release》(IF=9.776)上发表了题为“Imatinib Co-Loaded Targeted Realgar Nanocrystal for Synergistic Therapy of Chronic Myeloid L...
When you take a time-release drug, you count on it doing what the package says: release the drug slowly into your bloodstream to provide benefits over the specified period of time. When the drug disso...
近日,我校材料化学化工学部钟志远教授应Elsevier出版社和美国普渡大学教授Kinam Park主编的邀请,担任Journal of Controlled Release(JCR)亚洲区副主编。JCR是国际控制释放学会(Controlled Release Society)的官方杂志,影响因子7.901,是国际药剂学领域排名第一的专业期刊。钟志远教授研究领域涉及生物医用高分子材料、药物控制释放及...
Aquaporins (AQPs) play important role in the cerebrospinal fluid (CSF) secretion and AQP1 and AQP4 are localized in the choroid plexus (CP), which is the main place of CSF production. In ewes, season...
Drug treatments can save lives, but sometimes they also carry unintended costs. After all, the same therapeutics that target pathogens and tumors can also harm healthy cells.To reduce this collateral ...
Two experiments were performed to evaluate the effects of coated slow-release urea on nutrient digestion, ruminal fermentation, nitrogen utilization, blood glucose and urea concentration (Exp 1), and ...
Background: Capsaicin, which is the major pungent principle in chili peppers, is able to induce satiety and reduce caloric intake. The exact mechanism behind this satiating effect is still unknown. We...
This research analyzed the effect of β-glucan that is expected to alleviate the production of the inflammatory mediator in macrophagocytes, which are processed by the lipopolysaccharide (LPS) of Esche...
Recent findings have shown that microbial nitrogen flow and digestible energy of diets are increased when urea is combined with a slow-release urea (SRU) in diets with a starch to acid detergent fibre...
This study compared caffeine pharmacokinetics, glycerol concentrations, metabolic rate, and performance measures following ingestion of a time-release caffeine containing supplement (TRCAF) versus a...
Recently, slow release tablets have been developed to prolong energy release throughout the day. The efficacy of the delivery of slow-release caffeine alone is fairly well documented; however, an asse...
Volunteer smokers were randomly divided into four groups: group 1: VC supplement; group 2: exercise with VC supplement; group 3: exercise; and group 4: control. VC was prepared by wash and dry techn...
The effects of serotonin (5-HT), GnRH analogue (D-Ala6 LHRH, GnRH-A) and dopamine antagonist – pimozide (PIM), on luteinizing hormone (LH) release in mature Prussian carp female (Carassius gibel...

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