搜索结果: 1-15 共查到“cAMP”相关记录60条 . 查询时间(0.078 秒)
探讨蛋白激酶A(PKA)激活物cAMP对颅脑损伤(TBI)大鼠神经功能、脑水肿的影响。方法 选取120只成年雄性SD大鼠随机分为6组(每组20只):假手术组(暴露硬脑膜而不给予液压打击);高、中、低剂量cAMP组(TBI后1 h腹腔注射60、40、20 mg/kg PKA激活物8-Bromo-cAMP);溶媒组(TBI后1 h腹腔注射cAMP溶媒二甲基亚砜10 μl);模型组(液压打击处理)。TB...
Protein intake during training sessions has no effect on performance and recovery during a strenuous training camp for elite cyclists
Athletes Muscle damage Creatine kinase Power Endurance performance
2016/5/16
Background: Training camps for top-class endurance athletes place high physiological demands on the body.Focus on optimizing recovery between training sessions is necessary to minimize the risk of inj...
2015年9月29日,中国政府“友谊奖”颁奖大会在北京人民大会堂举行。国务院总理李克强2015年9月30日下午在人民大会堂会见荣获2015年度中国政府“友谊奖”的外国专家和他们的亲属。甘肃农业大学动物科学技术学院吴建平教授所领团队实施的“青藏高原牧区家庭牧场资源优化配置技术模式试验与示范”等引智项目所引进专家David Camp获此殊荣并受到国务院李克强总理的亲切接见。
Vitamin C, A and E supplementation decreases the expression of HSPA1A and HSPB1 genes in the leukocytes of young polish figure skaters during a 10-day training camp
HSPA1A HSPB1
2015/7/30
Overexpression of HSPA1A and HSPB1 has been shown to indicate stress and the degradation of damaged proteins. Therefore, the expression of these genes is often evaluated during exercise. Vitamin suppl...
Training Diaries during Altitude Training Camp in Two Olympic Champions: an Observational Case Study
Live high-train high live high-train low
2015/5/25
Traditionally, Live High-Train High (LHTH) interventions were
adopted when athletes trained and lived at altitude to try maximising the benefits offered by hypoxic exposure and improving
sea level...
为揭示LH/hCG受体和cAMP在玉米赤霉烯酮(ZEN)抑制小鼠睾丸间质细胞(leydig cells)分泌睾酮中的作用,本研究以原代培养的小鼠Leydig细胞为材料,用ELISA法分别测定ZEN暴露浓度为0、1、5、10、20 μg·mL-1及暴露时间为1、6、12、24 h时睾酮的分泌量(hCG环境及cAMP环境)和胞质内cAMP水平(hCG环境),用化学发光标记免疫分析法(CLIA)测定其细...
Misoprostol and the Sildenafil analog (PHAR-0099048) Modulate Cellular Efflux of cAMP and cGMP Differently
ABC-Transporters cAMP cGMP Misoprostol Sildenafil
2013/2/19
In the present study we have characterized ATP-dependent transport of cAMP and cGMP in physiological, but also supraphysiological concentrations. The uptake into inside-out vesicles from human erythro...
研究应用cAMP衍生物特异性激活Epac2/Akt信号通路在哺乳动物脊髓损伤中的病理和生理机制。 方法 96只成年健康雌性SD大鼠,完全随机分为4组(n=24),A、B、C组均采用改良Allen重物打击法制备大鼠脊髓损伤模型。A组给予8-CPT-2′-O-Me-cAMP 0.5 mg/(kg·d)、B组给予等量10%(体积分数)DMSO、C组给予8-CPT-2′-O-Me-c...
A Summer Pharmacy Camp for High School Students as a Pharmacy Student Recruitment Tool
pharmacy camp recruitment admissions pharmacy students survey
2018/6/6
Objective. To determine the effectiveness of a summer pharmacy camp on participants’ pursuit of enrollment in doctor of pharmacy degree programs.
Methods. All participants (n = 135) in a pharmacy cam...
色素上皮衍生因子对高糖诱导人肾小球系膜细胞p38丝裂原活化蛋白激酶-cAMP反应元件结合蛋白通路及纤连蛋白的影响
肾小球系膜细胞 p38丝裂原活化蛋白激酶类 cAMP反应元件结合蛋白质 纤连蛋白类 色素上皮衍生因子
2014/4/19
探讨色素上皮衍生因子(PEDF)对高糖条件下人肾小球系膜细胞(HMC)p38丝裂原活化蛋白激酶(p38MAPK)、cAMP反应元件结合蛋白(CREB)及细胞外基质成分纤连蛋白(FN)的影响。 方法 体外予正常糖(5.6 mmol/L)、甘露醇(24.4 mmol/L)、高糖(30 mmol/L)、高糖+PEDF(30 mmol/L葡萄糖+10 nmol/L、40 nmol/L、100 nmol/L...
探讨cAMP-PKA信号通路对细胞色素P4503A(CYP3A)在正常肝细胞L02表达中的作用。方法 L02细胞中分别加入8-溴-环腺苷酸(8-Br-cAMP)10 μmol·L-1及抑制剂H-89 10 μmol·L-1, 培养48 h, 分别采用完整细胞免疫组化法、Western印迹法和红霉素-N-脱甲基法检测细胞中PKA、孕烷X受体(PXR)及CYP3A的表达。结果 与正常对照组PKA蛋白表...
观察抑郁大鼠模型脑内环磷酸腺苷(cAMP)通路的表达及中药颐脑解郁方的干预作用。方法: Wistar大鼠分为正常组、模型组、中药颐脑解郁方组、西药氟西汀组。模型组、中药颐脑解郁方组、西药氟西汀组在 21 d内采用慢性不可预见的温和性应激加孤养法(method of chronic unpredictable mild stress with isolated support)建立抑郁状态大鼠模型,...
FSH通过cAMP、Ca2+调节仔猪睾丸支持细胞的增殖
促卵泡素 细胞增殖 睾丸支持细胞 细胞外调节的蛋白激酶1/2
2013/12/5
本研究旨在阐明FSH调节睾丸支持细胞增殖的机制。试验以2~3周龄的仔猪睾丸支持细胞为实验材料,采用体外培养模型,通过细胞数量检测、ELISA和Western blot等方法研究FSH对睾丸支持细胞的调节作用。试验结果如下:(1)在0~50 ng·mL-1内,随着FSH浓度的增加,睾丸支持细胞数量呈增加的趋势(P<0.05);当浓度为50 ng·mL-1时,FSH促增殖作用最明显;细胞内cAMP的浓...