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Pituitary-testicular function of prostatic cancer patients during treatment with a gonadotropin-releasing hormone agonist analog. II. Endocrinology and histology of the testis
Pituitary-testicular function prostatic cancer patients gonadotropin-releasing hormone
2009/2/23
Endogenous testosterone (T), LH and FSH receptors, and in vitro production of cyclic adenosine-3':5'-monophosphate (cAMP), T and some of its steroid precursors were measured in testicular tissue obt...
Pituitary-testicular function of prostatic cancer patients during treatment with a gonadotropin-releasing hormone agonist analog. I. Circulating hormone levels
Pituitary-testicular function prostatic cancer patients treatment gonadotropin-releasing hormone
2009/2/23
Eight patients with advanced prostatic carcinoma (ages 59 to 78 years) were treated with a potent gonadotropin-releasing hormone (GnRH) agonist analog (buserelin, Hoechst; 600 micrograms intranasall...
Reversal of testicular function after prolonged suppression with an LHRH agonist in rhesus monkeys
testicular function prolonged suppression LHRH agonist rhesus monkeys
2009/2/23
Using subcutaneously implanted osmotic pumps, four male rhesus monkeys were continuously infused for 18 months with 100 micrograms/day of [(imBzl)-D-His6-Pro9-NEt]-LHRH (LHRH-A), a potent agonist of...
Alterations of testicular function induced by hyperprolactinemia in the rat
testicular function hyperprolactinemia rat
2009/2/20
The effects of hyperprolactinemia on testicular structure and pituitary-gonadal function were investigated in male rats. Hyperprolactinemia was induced in the Wistar-Furth rat by implantation of t...
The effects of the indazole carboxylic acid derivative, tolnidamine, on testicular function：I. Early changes in androgen binding protein secretion in the rat
tolnidamine rABP LH FSH testosterone
2009/2/20
The indazole carboxylic acid derivative, tolnidamine, has marked antispermatogenic activity in several animal species. In this study, we assessed the effect of tolnidamine on rat Sertoli cell functi...
Effects of induced hypoprolactinemia on testicular function during gonadal maturation in the rat
testes androgens bromocriptine prolactin
2009/2/20
We have evaluated the effects of hypoprolactinemia during gonadal maturation in the male rat. Intact 30-day-old rats were injected daily for 10 days with three different doses of bromocriptine (0.75...
The effect of exogenous follicle stimulating hormone treatment on anterior pituitary and testicular function in the prepubertal bull
follicle stimulating hormone luteinizing hormone testosterone prepubertal bull
2009/2/20
The effect of exogenous follicle stimulating hormone (FSH) on testicular function was studied in twenty 4-month-old Holstein bulls during two seasons (ten in late winter and ten in summer). Five mg ...
Pituitary and testicular function in spontaneously hypertensive rats
Pituitary testicular function spontaneously hypertensive rats
2009/2/19
Levels of plasma gonadotropins, prolactin (PRL), and testosterone, and the testicular concentration, total content, and affinity of hCG binding sites were measured in male spontaneously hypertensi...
Effects of two non-steroidal antiandrogens on testicular function in prepubertal rats
Testis steroidogenesis flutamide casodex
2009/2/13
The effects of two non-steroidal antiandrogens, flutamide and casodex, were evaluated in prepubertal male rats. Animals (23 days old) were subcutaneously administered vehicle or 1, 2, 5, or 10 mg/...
Alterations of testicular function after induced autoimmune orchitis in rats
testicular function induced autoimmune orchitis rats
2009/2/12
The endocrinological profile of animals with experimental autoimmune orchitis (EAO) has not been sufficiently explored. With this purpose orchitis was induced in adult rats by active immunization ...
Effects of caudal elevation on testicular function in rats. Separation of effects on spermatogenesis and steroidogenesis
Hind-limb unloading testicular function testosterone spermatogenesis microgravity rats
2009/2/10
A variety of biologic processes are perturbed when exposed to microgravity (space flight) for more than 7 days, including testicular function. Suspension of rats in a special harness (caudal elevati...
Effects of subchronic treatment with cis-platinum on testicular function, fertility, pregnancy outcome, and progeny
Fertility cis-platinum pregnancy outcome progeny
2009/2/10
Cis-platinum-based chemotherapy is known to impair spermatogenesis, but the effects of paternal cis-platinum treatment on the progeny are unknown. To study this effect, sexually mature male Sprague-...
Assessment of the hypothalamic-pituitary-testicular function in male patients with Wilson's disease
Liver disease gonadotropins gonadotropinreleasing
2009/2/7
Sixteen male patients with Wilson's disease were studied to detect potential endocrine dysfunctions. There was no clinical evidence of feminization in any of the patients, and the patient group span...
Acute and chronic effects of cisplatinum upon testicular function in the rat
cisplatinum testis spermatogenesis Sertoli cell seminal vesicle
2009/2/6
One of the side effects of cisplatinum-based chemotherapy is the impairment of spermatogenic function. In order to understand the mechanisms responsible for this side effect, the present study exami...
Testicular function after local injection of 6-hydroxydopamine or norepinephrine in the golden hamster（Mesocricetus auratus）
golden hamster testis innervation norepinephrine 6-hydroxydopamine LH-receptors
2009/2/6
Although there is evidence for the sympathetic innervation of the mammalian testis, the function of noradrenergic fibers is not understood. This in vivo and in vitro study in the adult golden hamste...