搜索结果: 1-15 共查到“国际动态 人体免疫学”相关记录110条 . 查询时间(2.25 秒)
跨性别男性免疫反应差异需关注
免疫反应 激素 睾酮
2024/9/10
瑞典科学家研究发现，跨性别男性（出生性别女性）在性别肯定激素治疗期间，免疫反应会变得更像顺性别男性。这项分析涉及23名跨性别男性，凸显出性激素在免疫调节中的作用。这些发现对于进行性别肯定激素治疗的人的健康有影响，也能增进人们对顺性别个体免疫反应差异的理解。相关研究2024年9月4日发表于《自然》。
在淋巴结内发育而成—— “迷你肝脏”疗法开展人体试验 （图）
淋巴结 迷你肝脏 人体试验
2024/4/9
据《自然》网站2024年4月2日报道，一种在人体淋巴结内长出“迷你肝脏”的实验性疗法首次开展人体试验。研究团队正在12名晚期肝病患者身上测试该疗法，其中第一人于2024年3月25日接受治疗，目前表现良好。研究团队指出，如果几个月后观测结果显示该疗法有效，未来有望彻底改变肝病治疗现状。
章晓联课题组在病毒调控RIG-I通路介导免疫逃逸方向取得新成果（图）
武汉大学 基础医学 章晓联教授
2024/9/10
近日，武汉大学章晓联教授团队在国际学术期刊《自然·通讯》（Nature Communications, IF: 16.6）在线发表题为“EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I anti...
科学家发现延胡索酸诱导的线粒体相关先天免疫反应新机制
延胡索酸 线粒体 先天免疫反应
2024/1/16
肿瘤是一种由多因素驱动的疾病，不同恶性肿瘤有着共同的基本特征，其中细胞代谢重编程在恶性肿瘤发生发展中扮演重要角色。延胡索酸水化酶（fumarate hydratase，FH）是参与三羧酸循环中的代谢酶，被认为是一种肿瘤抑制因子。FH的突变可以导致延胡索酸盐的异常积累，通过一系列级联反应激活细胞恶性转化和肿瘤进展。近期，来自英国剑桥大学的科研团队在《Nature》上在线发表了题为“Fumarate ...
造血干细胞移植是许多恶性、遗传性或自身免疫性疾病的有效再生疗法。然而，目前人们对移植受者造血重建的了解仍然有限。近期，科学家在《Science Immunology》杂志发表题为“Single-cell dissection of human hematopoietic reconstitution after allogeneic hematopoietic stem cell transpla...
Researchers say we appear to be at the start of a new era for Alzheimer’s treatment. Trial results published in January showed that for the first time a drug has been able to slow the cognitive declin...
Chemists’ technique reveals whether antibodies neutralize SARS-CoV-2（图）
抗体 SARS-CoV-2 Covid-19
2023/6/7
Antibodies that can disarm a virus, known as neutralizing antibodies, are key to the body’s ability to fight off infection. MIT chemists have come up with a new way to identify these neutralizing anti...
The immune system does battle in the intestines to keep bacteria in check（图）
Research Infectious Diseases Veterinary Medicine
2023/6/29
Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis. A relative, Yersinia pseudotuberculosis, causes gastrointestinal illness...
2022年9月8日，中国医学科学院基础医学研究所暨中国医学科学院免疫治疗研究中心曹雪涛院士团队在Cancer Cell在线发表了题为“Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance”...
It’s been known for decades that astronauts’ immune systems become suppressed in space, leaving them vulnerable to disease, but the exact mechanisms of immune dysfunction have remained a mystery – now...
Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions.
2022年4月9日，中国医学科学院基础医学研究所许群团队在环境保护领域主流杂志Environment International上发表题为“Do urinary metals associate with the homeostasis of inflammatory mediators? Results from the perspective of inflammatory signaling...
The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflamma...
Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer...
Immunotherapy is a promising strategy to treat cancer by stimulating the body’s own immune system to destroy tumor cells, but it only works for a handful of cancers. MIT researchers have now discovere...