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采用口服肾上腺皮质激素的方法在国产昆明小鼠成功诱导卡氏肺孢子虫感染。在54只实验鼠中,47只发现虫体,阳性率为87.03%。表明该方法可适用于建立卡氏肺孢子虫感染的小鼠动物模型,并具有简便、经济等优点。
Background: Drug-induced hypersensitivity syndrome (DIHS) is characterized by a severe multiorgan hypersensitivity reaction that usually appears after prolonged exposure to certain drugs and may be re...
世界卫生组织癌症研究合作中心全年通过各种渠道共组织申报课题84项,目前已知中标8项。获得海外杰出青年基金1项,863纳米专项1项。
癌症严重危害了广东人民的健康和生命,已引起政府和全省人民的关注。根据70年代的全人口全死因调查和80年代,90年代的抽样调查资料表明,广东省每年新癌症病人达9万,死亡7万,现有癌症病人13万。为了防治癌症,保护劳动生产力,促进经济和社会的发展,我合作中心紧紧依靠省卫生厅和各级政府有关部门,广泛开展防癌宣传教育、提高全民防癌意识,从而加强了癌症的控制。
Experimental allergic encephalomyelitis (EAE), a demyelinating disease induced in the animals parallels multiple sclerosis in human in several aspects, provides a useful model to investigate multiple ...
The presence of IgE antibodies to the allergens rBetv1 and rBetv2 was investigated in the sera of 99 patients with specific IgE to apple extract by comparing a group of 43 patients who had oral allerg...
The small airway disease in asthma is characterized by airway wall thickening associated with eosinophilic inflammation and hypervascularity. In our study, predicted forced expiratory volume in 1 s (%...
In patients with persistent asthma who require inhaled short-acting β2-agonists while receiving inhaled corticosteroids, transdermal tulobuterol significantly improved PEF in a dose-dependent manner, ...
Background: The purpose of present study is to determine the value of serum levels of the soluble form of β2 integrin-associated glycosylphosphatidylinositol (GPI)-anchored glycoprotein (GPI-80) for m...
Hydatidosis is one of the major zoonotic diseases that cause considerable economic losses and public health problems worldwide. The present study was conducted to determine the prevalence of E. granul...
Mazandaran province, northern Iran, has been an area with highest prevalence of infectivity with human taeniasis during past decades. In order to assess current situation of taeniasis in the province ...
Municipal wastewater is one of the most important pollution sources for water supply resources. Identification and enumeration of pathogenic agents particularly pathogenic Vibrios are beneficial for c...
Alzheimer’s disease (AD) is a uniquely human disorder. Although the pathogenesis of AD is not fully understood, growing evidence indicates that the deposition of beta-amyloid (Aβ) and the local reacti...
Leptin affects paraventricular nucleus of hypothalamus and reduces appetite while activation of α2-adrenoceptors at this site has opposite action. The reducing effect of α2-adrenoceptors inhibition on...
利用纳米技术进行恶性肿瘤早期诊断和治疗是目前国际生物技术领域中最前沿的研究课题,迄今实验室细胞模型(in vitro)研究和临床前动物模型(in vivo)研究已取得了重大进展.纳米生物技术将成为继放疗、化疗和手术治疗后治疗基因疾病的更有效的方法.纳米生物技术涵盖纳米材料科学,构成纳米药物载体平台的纳米材料与药物或基因结合的组装技术以及随后与靶向物质结合的组装技术.目前,实现了纳米生物传感器在肿瘤...

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