搜索结果: 1-15 共查到“知识库 药物统计学”相关记录23条 . 查询时间(5.164 秒)
Pharmacy Preceptor Judgments of Student Performance and Behavior During Experiential Training
experiential learning workplace-based assessment preceptor judgments
2019/1/7
Objective. To report the findings of how Canadian preceptors perceive and subsequently evaluate diverse levels of trainees during pharmacy clerkships.Methods. Using modified Delphi technique, 17 Docto...
Impact of Time Allocation Practices on Academic Outcomes for Students from a 2-Campus Pharmacy School
distance education satellite time allocation
2018/7/24
Objective: To assess how students from 2 campuses spent their time during P1-P3 (first through third) years, and whether that time allocation impacted their APPE grades and NAPLEX performance.
Method...
A Flowchart for Selecting an Ointment Base
compounding nonsterile compounding ointment decision-making flowchart
2018/7/2
Objectives. To improve students’ skills in selecting appropriate ointment bases through the development and implementation of a flowchart.
Design. A flowchart was designed to help students select the...
3-正丁基苯酞大鼠在体肠吸收动力学
3-正丁基苯酞 在体单向肠灌流模型 吸收
2013/9/6
研究3-正丁基苯酞(NBP)在大鼠各肠段的吸收动力学特征。 方法: 采用大鼠在体肠段灌流实验,利用紫外分光光度法和HPLC法分别测定酚红和3-正丁基苯酞的量,分别研究药物质量浓度和羟丙基-β-环糊精(HPCD)用量对3-正丁基苯酞吸收的影响。 结果: 在1,10,100 mg·L-1药物质量浓度对各肠段的表观吸收系数(Papp)无明显影响;灌流液中随HPCD用量的增加对NBP在大鼠肠黏膜的吸收抑制...
Interprofessional Workshop to Improve Mutual Understanding Between Pharmacy and Medical Students
interprofessional education interdisciplinary education health profession students
2018/6/12
Objective. To measure changes in pharmacy and medical students’ physician-pharmacist collaboration scores resulting from a workshop designed to promote understanding of the others’ roles in health car...
塞来昔布对人乳腺癌SKBR-3细胞生长的影响
乳腺癌 SKBR-3 塞来昔布 环氧化酶-2(COX-2)
2012/11/1
探讨选择性环氧化酶-2(COX-2)抑制剂塞来昔布对乳腺癌SKBR-3细胞生长的影响及机制。方法 用不同浓度的塞来昔布处理SKBR-3细胞后，采用CCK-8 法检测塞来昔布对SKBR-3细胞增殖活性的影响；流式细胞仪检测细胞周期；酶联免疫吸附试验(ELISA)检测前列腺素E2(PGE2)的释放水平；Western Blot法测定各浓度塞来昔布刺激SKBR-3细胞后Caspase-3被酶解激活情况。...
基于"组分构成"理论的中药质量控制新思路
中药多维结构质量控制体系 组分构成 量化配比结构 量效关系 可控范围窗
2012/4/26
建立合理准确乃至符合中医基础理论可量化的中药质量评价体系是现代中药国际化发展道路上的一大关键问题。作者基于对中药组分作用整体性的认识,提出将"组分构成"理论的思想植入到中药多维结构质量控制体系中,强调中药是基于组分间及组分内部各成分间特定的微观结构关系而发挥多靶点、多途径药效作用的。目前《中国药典》主要依靠控制中药单一/多个指标性成分含量来把关中药质量。事实上,只针对中药指标性成分的控制完全脱离了...
评价几条热点DNA条形码候选序列对马鞭草科药用植物的鉴别能力。 方法: 选择psbA-trnH,rbcL,matK,ITS2和ITS序列进行评价,使用各序列的通用引物进行扩增和测序,用扩增及测序成功率,种内种间差异,barcoding gap,基于BLAST 1和Nearest Distance方法的鉴定成功率等指标来评价各序列的鉴定能力。 结果: 对马鞭草科32个种55个样本的序列分析发现,ma...
简捷实用的半数致死量综合计算法
半数致死量综合计算法
2009/12/1
本文根据适当的实驗設計即:(1)各組动物数相同;(2)剂量成等比級数;(3)反应情况大致符合常态分布;(4)实驗例包括或接近0%及100%反应率,簡化并改进了Kaerber法,又結合了Bliss几率单位法的特点,提出一种甚为簡捷而又相当准确的半数致死量計算法。文中通过数理論証和实例校算証明了本法在簡捷度上优于Reed-Muench法,Kaerber原法及:Thompson法。在精确度上亦較Kaer...
为了建立一种新型氨基酸结构描述子并用于多肽定量构效关系研究，本研究从天然氨基酸150个radial distribution function (RDF)指数经主成分分析得出一种新3D氨基酸描述子-SVRDF(principal component scores vector of radial distribution function)，应用该描述子并通过偏最小二乘(PLS)对苦味二肽、催产素...
本文运用了统计矩原理阐明并建立中药复方多成分指纹图谱定性定量分析法：总量统计矩方法。包括4个参数： ① 总零阶矩AUCT； ② 总响应率AUCPWT； ③ 总量一阶矩MCRTT，亦总量中心矩或总量平均保留时间，用T表示； ④ 总体二阶矩VCRTT，亦为平均保留时间方差，用2T表示。AUCT能用于中药复方指纹图谱定量分析，AUCPWT、MCRTT、VCRTT能用于中药复方指纹图谱定性分析。以此法研究...
反义寡核苷酸的药代动力学研究进展
反义 寡核苷酸 药代动力学
2009/11/16
反义药物在经历了20年后，又迎来了一个蓬勃的发展阶段。研究结果表明，反义药物在抗肿瘤、抗炎和抗病毒等方面展现出令人鼓舞的前景，反义寡核苷酸可能成为新药开发新的生长点。本文调查了近年反义寡核苷酸药代动力学的研究进展，对反义寡核苷酸的吸收、分布、代谢和排泄进行了详细的综述。
Barriers to Expanding Advanced Pharmacy Practice Experience Site Availability in an Experiential Education Consortium
consortium practice experience pharmacist shortage preceptors
2018/5/14
Objectives. To compare 2006–2007 and projected 2010–2011 advanced pharmacy practice experience (APPE) availability and needs for 4 colleges and schools of pharmacy in Georgia and Alabama and to examin...
Perceived Barriers to Scholarship and Research Among Pharmacy Practice Faculty: Survey Report from the AACP Scholarship/Research Faculty Development Task Force
scholarship research barriers faculty faculty development pharmacy practice
2018/5/8
Objectives. To identify problems that pharmacy practice faculty members face in pursuing scholarship and to develop and recommend solutions.
Methods. Department chairs were asked to forward a Web-bas...
葡萄球菌属对常用抗生素耐药情况调查
2007/7/25
葡萄球菌(主要是金黄色葡萄球菌，简称金葡萄、表皮葡萄球菌)是我院临床标本分离细菌中的主要病原菌，也是近年来引起医院内感染的主要细菌。耐甲氧西林葡萄球菌(methicillin-resistant Staphylococcus, MRS)有很高的耐药率和多重耐药性，给临床治疗带来相当大的困难。因此，及时了解与分析它对常用抗生素的耐药情况，可为临床选择用药提供参考。