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Timing of Alcohol and Other Drug Use And Sexual Risk Behaviors Among Unmarried Adolescents and Young Adults
Drug Use Young Adults Alcohol Unmarried Adolescents
2009/9/16
Context: Although alcohol and drug use by young people has been associated with sexual risk behavior in some research, detailed data are lacking on the timing of substance use in relationship to sexua...
Drug Binding and Releasing Characteristics of DNA/Lipid/PLGA Film
Intercalation DDS DNA/lipid/PLGA film
2009/9/14
We evaluated the blended compound of DNA/lipid complexes and PLGA (poly(D,L-lactide-co-glycolide)) as a carrier material for drug delivery system (DDS). Transparent, self-standing DNA/lipid/PLGA films...
Development of New Drug Delivery System for Implant Bone Augmentation Using a basic Fibroblast Growth Factor-gelatin Hydrogel Complex
bFGF-gelatin hydrogel complex Drug delivery system Implant bone augmentation
2009/9/14
This study sought to clarify the effectiveness of bFGF-gelatin hydrogel complex on bone regeneration around implants for the development of a new drug delivery system for bone augmentation. Twenty-fou...
A new way to prepare fluorinated pharmaceuticals--New method gives drug designers more flexibility
fluorinated pharmaceuticals drug designers new method
2009/8/18
A team of MIT chemists has devised a new way to add fluorine to a variety of compounds used in many drugs and agricultural chemicals, an advance that could offer more flexibility and potential cost-sa...
Effects of helium-oxygen and hyperbaric helium-oxygen environment on drug-metabolizing enzyme activity in rat liver
heliox drug enzymology Cocaine Morphine O-Demethylase animal rat
2009/7/15
The effects of room-air normoxic (22 degrees C +/- 1 degree C), 1.2-ATA He-O2 (400 mmHg PO2, 29.0 degree C +/- 1 degree C), and 21-ATA He-O2 (400 mmHg PO2, 32.5 degrees C +/- 1 degree C) environments ...
Meta-Analysis of Quality of Life Constructs in Antihypertansive Drug Theraphies
Meta-analysis Antihypertansive Drug Therapy Hypertension Quality of life Clinical Trials
2009/7/1
Objectives:It is usually accepted that some of the treatments affect not only the survival times but as well the quality of life of patients. The aim of study is to reach more reliable conclusions by ...
The in Vitro Effects of The Antimalarial Drug Primaquine,on The Activities of Some Enzymes in Human Erythrocyte Lyzates
Primaquine inhibition glucose-6- phosphate dehydrogenase catalase glutathione peroxidase superoxide dismutase glutathione reductase glutathione transferase
2009/7/1
The effect of primaquine on the enzymatic antioxidant defence mechanisms of erythrocytes were determined by measuring the activities of the below enzymes, before and after 30 minutes of incubation of ...
Preparation of PHBV Foams and Investigation of Their Potential For Drug Release
Controlled Release Poly(hydroxybutyrate-co-hydroxyvalerate)-PHBV Polymer foams Tetracycline
2009/6/30
Polymeric foams seem to have potential for use in many research areas such as cell seeding and macromolecule or drug loading. Three factors were studied to evaluate the efficiency of foams as drug car...
Lamotrigine Treatment in Childhood Drug-Resistant Epilepsy
Lamotrigine drug resistant epilepsy intractable epilepsy
2009/6/30
Rationale: In this study the efficacy of Lamotrigine was evaluated in children with medically intractable epilepsy. Methods: 22 epileptic children, ranging between 4.2 years and 15 years of age (mean ...
Biosynthesis of Polyhydroxybutyrate and its Copolymers and Their Use in Controlled Drug Release
polyhydroxyalkanoates Alcaligenes latus Alcaligenes eutrophus osteomyelitis controlled drug delivery
2009/6/29
Our aim was to prepare antibiotic loaded rods with biotechnologically produced biodegradable polymers and use them in the treatment of osteomyelitis by providing a high local dose of antibiotic at the...
Colicinogeny,Lipopolysaccharide and Outer Membrane Protein Profiles of Multi-Drug Resistant Salmonella typhimurium Isolates from Turkey
Salmonella Colicin production LPS OMP plasmid
2009/6/25
A total of 259 clinical isolates of non-repetitive non-typhi salmonellae (NTS) were previously examined for their antibiotic resistance patterns and plasmid contents. Multi-drug resistant strains comp...
Drug Resistance in Acute Leukaemia and Reversion
Drug Resistance Acute Leukaemia Reversion
2009/6/24
Haematological neoplasms are usually primarily sensitive to chemotherapy, but the relapse rate is still high, except for HodgkinÕs lymphoma and childhood acute lymphoblastic leukaemia (ALL). Dr...
Genotoxic Evaluation of the Antibacterial Drug,Ciprofloxacin,in Cultured Lymphocytes of Patients with Urinary Tract Infection
Ciprofloxacin sister chromatid exchange mitotic index replicative index
2009/6/23
Ciprofloxacin is a quinolone carboxylic acid derivative and is commonly used in medicine. The genotoxicity of ciprofloxacin was evaluated in cultured human peripheral blood lymphocytes in patients wit...
Quality Control Studies on Conventional Carbamazepine Tablets Available on the Turkish Drug Market
Conventional carbamazepine tablets quality control studies
2009/6/22
Carbamazepine (CBZ) is a widely used antiepileptic drug. It is used to control grandmal seizure as well as in the treatment of neuralgia. The drug is characterised by slow and irregular gastrointestin...
Effects of Direct Tabletting Agents on Drug Release Kinetics and Swelling Behavior of Hydrophilic Matrix Tablets
Hydroxypropyl-methylcellulose Direct tabletting agents Matrix tablet Swelling degree Verapamil hydrochloride
2009/6/19
Aims: This work focused on the effects of direct tabletting agents (DC-agents) (Microcel PH101®, Cellactose 80®, Ludipress LCE®, Pharmatose DCL11®) and hydroxypropyl-methylcellulose (H...