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Infant weight at birth, a major determinant of short- and longterm
health, is influenced by genetic factors, maternal body size,
and intrauterine substrate supply and metabolism (1). Two articles
i...
Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n−3 or n−6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y
Fish oil immunity natural killer cell
2016/6/12
Animal studies showed that dietary flaxseed oil
[rich in the n3 polyunsaturated fatty acid -linolenic acid
(ALA)], evening primrose oil [rich in the n6 polyunsaturated
fatty acid -linolenic acid (...
Effect of 6 dietary fatty acids on the postprandial lipid profile, plasma fatty acids, lipoprotein lipase, and cholesterol ester transfer activities in healthy young men
PUFA saturated fatty acids SFA
2016/6/12
There is increasing evidence that postprandial triacylglycerol-rich
lipoproteins may be related to atherogenic risk.
Impairment of lysophospholipid metabolism in obesity: altered plasma profile and desensitization to the modulatory properties of n–3 polyunsaturated fatty acids in a randomized controlled trial
DHA EPA nflammation men and women randomized controlled trial risk factors
2018/12/3
Background: To date, most studies on the anti-inflammatory effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in humans have used a mixture of the 2 fatty acids in various forms and...
Assorted monounsaturated fatty acids promote healthy hearts
monounsaturated fatty acids healthy hearts
2016/6/2
In the last half of this century, a variety of recommendations
have been made concerning the optimal diet to lower cardiovascular
disease (CVD) risk. The primary focus in the early years
was on dec...
Harbingers of coronary heart disease: dietary saturated fatty acids and cholesterol. Is chocolate benign because of its stearic acid content?
fatty acids cholesterol
2016/6/2
Consumption of foods rich in saturated fatty acids and cholesterol
has long been recognized as an important precursor for the
development of coronary heart disease; saturated fatty acids and
choles...
Effect of trans fatty acids on calcium influx into human arterial endothelial cells
atherosclerosis umbilical cord magnesium
2016/6/1
A recent task force of The American Society for
Clinical Nutrition and American Society for Nutritional Sciences
recommended in a position paper on trans fatty acids that
models be developed to ass...
Receptor-mediated signaling pathways: potential targets of modulation by dietary fatty acids
dietary fat tyrosine kinase protein kinase
2016/6/1
Extracellular signals are transmitted to intracellular
targets through many signal-transduction pathways. Each
signaling pathway is composed of a network of interacting signaling
molecules that reg...
Human beings evolved consuming a diet that contained
about equal amounts of n23 and n26 essential fatty acids.
Over the past 100–150 y there has been an enormous increase in the
consumption of n26 ...
trans Fatty acids in human milk are inversely associated with concentrations of essential all-cis n−6 and n−3 fatty acids and determine trans, but not n−6 and n−3, fatty acids in plasma lipids of breast-fed infants
human milk breast-fed infants breast milk
2016/6/1
Human milk fatty acids vary with maternal dietary
fat composition. Hydrogenated dietary oils with trans fatty acids
may displace cis n26 and n23 unsaturated fatty acids or have
adverse effects on t...
Heart rate variability and fatty acid content of blood cell membranes: a dose-response study with n−3 fatty acids
sudden cardiac death cardiac arrest ventricular arrhythmias
2016/6/1
Dietary intake of long-chain n23 polyunsaturated
fatty acids (PUFA) may protect against sudden cardiac
death, an event that may be predicted by measurement of heart
rate variability (HRV).
Plasma lipoprotein fatty acids are altered by the positional distribution of fatty acids in infant formula triacylglycerols and human milk
triacylglycerol structure fatty acids chylomicron
2016/5/31
Triacylglycerol digestion involves hydrolysis of
fatty acids esterified at the glycerol 1,3 positions by gastric and
pancreatic lipase to produce 2-monoacylglycerols and unesterified
fatty acids, w...
Maternal plasma phospholipid polyunsaturated fatty acids in pregnancy with and without gestational diabetes mellitus: relations with maternal factors
insulin resistance gestational diabetes mellitus pregnancy
2016/5/31
The fatty acids arachidonic acid (AA; 20:4n26)
and docosahexaenoic acid (DHA; 22:6n23) are essential for
fetal growth and development, but their metabolism may be
altered in insulin resistance
Differential effects of saturated and monounsaturated fatty acids on postprandial lipemia and incretin responses in healthy subjects
Saturated fat monounsaturated fat oleic acid
2016/5/31
Elevations of postprandial triacylglycerol-rich
plasma lipoproteins and suppressions of HDL-cholesterol concentrations
are considered potentially atherogenic. Long-term studies
have shown beneficia...
Umbilical vessels of preeclamptic women have low contents of both n−3 and n−6 long-chain polyunsaturated fatty acids
Preeclampsia fatty acids umbilical vessels
2016/5/30
Preeclampsia is characterized by enhanced platelet aggregation and vasoconstriction and is related to an elevated ratio of thromboxane A2 to prostacyclin I2.