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Relationship between Serum Umbilical Cord and Maternal Leptin and Adiponectin Concentrations with Fetal Growth Parameters
Serum umbilical Maternal leptin Fetal growth
2010/4/9
Background: Pregnancy and accelerated fetal growth always are related with major metabolic changes and body fat redistribution and adiponectin is one of principle adipocyte hormones, so studying adipo...
肠缺血/再灌注损伤对leptin及orexin-A水平的影响
2007/7/25
Leptin亦称瘦素、消脂素，是一种包含167个氨基酸、相对分子质量为16 000的脂肪细胞特异性分泌的蛋白，它由ob基因受神经-内分泌系统和能量代谢状况的反馈调节而表达，通过与位于下丘脑的特异受体结合而发挥抑制摄食和促进能量消耗的主要作用[1]。此外，leptin还参与造血、生殖、血管生成及免疫应答[2]。Orexin-A亦称为hypocretin-1，是一种由下丘脑侧部特异神经元分泌的短肽，它...
EFFECTS OF YOHIMBINE ON PLASMA LEVELS OF LEPTIN IN NORMAL AND STREPTOZOTOCIN INDUCED DIABETIC RATS
Diabetic rats leptin yohimbine insulin adrenoceptor streptozotocin
2010/2/4
Leptin affects paraventricular nucleus of hypothalamus and reduces appetite while activation of α2-adrenoceptors at this site has opposite action. The reducing effect of α2-adrenoceptors inhibition on...
Pegylated human recombinant leptin (PEG-OB) causes additional weight loss in severely energy-restricted, overweight men
polyethylene glycol–OB protein PEG-OB semistarvation
2016/12/30
Increasing evidence suggests that falling leptin concentrations observed during fasting act as a peripheral signal of starvation, which serves to conserve energy in the face of limited reserves. An ex...
Leptin and energy metabolism in pulmonary tuberculosis
Basal metabolism body composition cytokines
2016/12/29
Pulmonary tuberculosis is the classic cause of “consumption,” but the pathogenesis of such wasting is largely unknown. Animal studies in other conditions suggest that leptin may be a mediator between ...
Early nutrition and leptin concentrations in later life
Leptin obesity breast-feeding formula feeding adolescents preterm infants fat mass
2016/12/17
Background: Formula feeding or overweight in infancy may increase the later risk of obesity, but the mechanisms involved are uncertain. Because obesity is associated with high leptin concentratio...
Patterns of plasma leptin and insulin concentrations in hospitalized patients after the initiation of total parenteral nutrition
Total parenteral nutrition TPN leptin insulin fasting critical illness cytokines sex differences body mass
2016/12/17
Background: The regulation of leptin in patients with critical illness is poorly understood. Sex, diet, body mass, and cytokines may all play a role.Objective: The aims of this study were to...
Resting metabolic rate,plasma leptin concentrations,leptin receptor expression,and adipose tissue measured by whole-body magnetic resonance imaging in women with Prader-Willi syndrome
Magnetic resonance imaging MRI obesity body fat Prader-Willi syndrome fat distribution resting metabolic rate growth hormone deficiency hypogonadism women
2016/12/17
Background: Obesity in Prader-Willi syndrome (PWS) may be related to abnormalities in the adipocyte-leptin-hypothalamic pathway and may be exacerbated by reductions in the resting metabolic rate ...
Leptin and maternal growth during adolescent pregnancy
Adolescent pregnancy leptin growth birth weight low birth weight fetal grow restriction body composition
2016/6/8
Background: Maternal growth on the basis of knee height
occurs in nearly 50% of pregnant teenagers and is associated
with greater gestational weight gain and accrual of subcutaneous
fat in the moth...
Serum leptin concentrations in infants: effects of diet, sex, and adiposity
Leptin infants milk formula breast-feeding, adiposity sex
2016/6/7
Background: Leptin, the product of the obese (ob) gene, is a
regulator of food intake and energy metabolism. Immunoreactive
leptin was detected recently in breast milk and it has been
hypothesized ...
Basal metabolic rate in anorexia nervosa: relation to body composition and leptin concentrations
Basal metabolic rate leptin body composition, fat-free mass anorexia nervosa Italy women
2016/6/7
Background: Leptin is thought to represent a peripheral signal
involved in the regulation of energy balance. Its action has been
studied in animals and obese subjects. Little is known about leptin’s...
Short-term, high-fat diets lower circulating leptin concentrations in rats
Energy intake satiety leptin body weight, high-fat diet adipose tissue rats
2016/6/3
Background: Leptin is produced in proportion to body fat mass
and can act on the brain to induce satiety and regulate adipose
tissue mass; factors other than adipose tissue mass may influence
circu...