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Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids
fat malabsorption fat balance lipolysis
2016/5/27
Pancreatic enzyme replacement therapy frequently
fails to correct intestinal fat malabsorption completely in
cystic fibrosis (CF) patients. The reason for this failure is
unknown.
Serum n–6 polyunsaturated fatty acids, Δ5- and Δ6-desaturase activities, and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
polyunsaturated fatty acids desaturase enzymes serum zinc type 2 diabetes prospective study
2018/11/30
Background: The role of n–6 (ω-6) polyunsaturated fatty acids (PUFAs) in type 2 diabetes (T2D) is inconclusive. In addition, little is known about how factors involved in PUFA metabolism, such as zinc...
The association between dietary saturated fatty acids and ischemic heart disease depends on the type and source of fatty acid in the European Prospective Investigation into Cancer and Nutrition–Netherlands cohort,
saturated fatty acids ischemic heart disease nutrition epidemiology follow-up studies
2018/11/27
Background: The association between saturated fatty acid (SFA) intake and ischemic heart disease (IHD) risk is debated.
Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium
DNA methylation epidemiology fatty acids genetic variants plasma lipids
2018/11/28
Background: DNA methylation is influenced by diet and single nucleotide polymorphisms (SNPs), and methylation modulates gene expression.
Microencapsulated foods as a functional delivery vehicle for omega-3 fatty acids:a pilot study
Microencapsulated foods functional delivery vehicle omega-3 fatty acids
2015/7/16
It is well established that the ingestion of the omega-3 (N3) fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) positively benefit a variety of health indices. Despite these benef...
The Effect of Omega-3 Fatty Acids on Airway Inflammation, Hyperpnea-Induced Bronchoconstriction, and Airway Smooth Muscle Contractility in Asthma
Asthma Bronchoconstriction Fish Oil
2015/5/22
Asthma, a chronic inflammatory disease of the airways, affects nearly 25 million Americans. The vast majority of these patients suffer from exercise-induced bronchoconstriction (EIB), a complication o...
EFFECTS OF OMEGA-3 FATTY ACIDS ON RODENT MODELS OF BIPOLAR DISORDER AND ALCOHOLISM
Omega-3 bipolar alcoholism DBP mouse P rat genomics DHA
2015/5/21
Our laboratory has previously identified the clock gene D-box Binding Protein (DBP) as a candidate gene for bipolar disorder and alcoholism using a Convergent Functional Genomics (CFG) approach. In su...
Prenatal exposure to methyl mercury from fish consumption and polyunsaturated fatty acids: associations with child development at 20 mo of age in an observational study in the Republic of Seychelles
child development maternal fish consumption methyl mercury polyunsaturated fatty acids docosahexaenoic acid arachidonic acid n–6:n–3
2018/12/24
Background: Fish is a rich source of n–3 polyunsaturated fatty acids (PUFAs) but also contains the neurotoxicant methyl mercury (MeHg). PUFAs may modify the relation between prenatal MeHg exposure and...
Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study
diabetes mellitus fatty acids metabolism biomarker diet
2018/12/20
Background: Experimental evidence suggests that hepatic de novo lipogenesis (DNL) affects insulin homeostasis via synthesis of saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs). Few...
The Effect of Unsaturated Fatty Acids on Molecular Markers of Cholesterol Homeostasis in THP-1 Macrophages
Atherosclerosis Macrophages Receptors Oxidized LDL Peroxisome Proliferator-Activated Receptors
2015/9/30
Background: Macrophages derived foam cells are key factors in the maladaptive immune and inflammatory response.
Efficacy of omega-3 fatty acids supplementation in treatment of uremic pruritus in hemodialysis patients: a double-blind randomized controlled trial
Fatty Acids Omega-3 Fish Oils pruritus Renal Dialysis Uremia
2015/9/28
Background: Uremic pruritus is a common and bothersome complaint among end-stage renal disease which affect between 25% and 60% of this population .But there is no decisive cure for treatment of it. I...
Effect of long-chain n23 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism
Triacylglycerol postprandial lipemia n23 polyunsaturated fatty acids PUFAs fish oil eicosapentaenoic acid EPA docosahexaenoic acid DHA coronary heart disease
2016/6/3
Elevated plasma triacylglycerol concentrations
have been associated with increased risk of coronary heart disease
(CHD). In the past, the epidemiologic evidence about the
causal role of triacylglyc...
SOME EFFECTS OF ORAL CONTRACEPTIVES ON SERUM FATTY ACIDS DISTRIBUTION
Serum total fatty acids Oral contraceptives Eugynon Lyndiol
2009/12/31
Serum total fatty acids were estimated in controls and women using the oral contraceptives Eugynon (containing 0.5 mg.of norgestron and 0.05 mg ethinyl oestradiol) and Lyndiol (containing 2.5 mg. of l...
ANALYSIS OF CONTRASTING EFFECTS OF ALLOXAN AND MAGNESIUM ON PLASMA FREE FATTY ACIDS (FFA) IN DIABETES INDUCED RATS
Magnesium Free Fatty Acids DIABETES
2009/12/31
Background: Alloxan is on of the xenobiotic agents which is classified as diabetogenic materials. Magnesium is an important cofactor regulating the activity of carbohydrate enzymes and lipid synthesis...
A GAS CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF INDIVIDUAL FREE FATTY ACIDS IN SERUM
Serum fatty acids Gas chromatographic method
2009/12/30
Serum fatty acids on 30 healthy lranian women were detemined by a gas chromatographic method. Oleic and stearic acids were used as standards. The mean values were myristic acid 5. 7% , palmitic acid 4...