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Omega-3 long-chain PUFA intake during pregnancy and allergic disease outcomes in the offspring: a systematic review and meta-analysis of observational studies and randomized controlled trials
allergic disease n–3 LC-PUFA pregnancy allergy prevention fatty acids randomized controlled trial prenatal supplementation asthma eczema hayfever
2018/11/23
Background: There is some evidence that increased maternal intake of omega-3 (n–3) long-chain polyunsaturated fatty acids (LC-PUFAs) during pregnancy may reduce the incidence of immunoglobulin E (IgE)...
TGF-β Signaling May Play a Role in the Development of Goblet Cell Hyperplasia in a Mouse Model of Allergic Rhinitis
allergic rhinitis epithelial cells Smad TGF-β
2010/11/12
In the mouse model of allergic rhinitis, OVA challenge induced phosphorylation of Smad2 predominantly in epithelial cells in the nasal mucosa. In addition, the administration of an inhibitor of TGF-β ...
Case Report of Restoration of the Corneal Epithelium in a Patient with Atopic Keratoconjunctivitis Resulting in Amelioration of Ocular Allergic Inflammation
allergic inflammation atopic keratoconjunctivitis conjunctiva corneal ulcer epithelium
2010/11/12
Background: Atopic and vernal keratoconjunctivitis are severe types of ocular allergic disease characterized not only by conjunctival inflammation but also by corneal involvement. In vitro studies hav...
Comparative efficacy of caffeic acid phenethyl ester (CAPE), olopatadine hydrochloride, and dexamethasone sodium phosphate in experimental allergic conjunctivitis
Allergic conjunctivitis caffeic acid phenethyl ester dexamethasone sodium phosphate olopatadine hydrochloride
2010/10/14
To compare the antiallergic efficacy of 1% caffeic acid phenethyl ester (CAPE), 0.1% olopatadine hydrochloride, and 0.1% dexamethasone sodium phosphate. Materials and methods: Experimental allergic co...
Importance of IL-18-Induced Super Th1 Cells for the Development of Allergic Inflammation
allergic inflammation atopic dermatitis bronchial asthma IL-18 super Th1
2010/11/12
Th1 cells, which express IL-18R, produce IFN-γ in response to Ag and IL-2 and increase further production of IFN-γ upon additional IL-18 stimulation. They simultaneously produce Th2 cytokines (IL-9 an...
Alarming Dendritic Cells for Allergic Sensitization
alarmins asthma danger signals dendritic cells IL-1
2010/11/12
Allergic patients mount a Th2 response to common allergens, like house dust mite (HDM), pollens, molds and animal dander. Most inhaled antigens are immunologically inert, however if these antigens are...
Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
airway hyperreactivity asthma prevention Th2 cell tomato extract
2010/11/12
Background: Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes. In this study, we investigated the effect of n...
Antigen-Specific Immunotherapy against Allergic Rhinitis: The State of the Art
allergic rhinitis biomarker immunotherapy pollinosis regulatory T cell
2010/11/12
Allergic rhinitis is the most prevalent type I allergy in industrialized countries. Pollen scattering from trees or grasses often induces seasonal allergic rhinitis, which is known as pollinosis or ha...
Determination the best cereal substitute for wheat in wheat allergic children
Food allergy Wheat Wheat allergy
2010/1/5
Background: Food allergy is one of the most important among other allergic diseases. Although it is less prevalent in adult but in infants it’s prevalence was reported as much as 8 percent. In part, w...
Evaluation of Novel Scoring System Named 5-5-5 Exacerbation Grading Scale for Allergic Conjunctivitis Disease
allergic conjunctivitis atopic keratoconjunctivitis clinical severity score vernal keratoconjunctivitis
2010/11/16
The median severity scores of the 5-5-5 exacerbation grading scale in VKC, AKC and AC were 243 (range: 12-444), 32.5 (11-344), and 13 (2-33), respectively. The severity score of each ACD disease type ...
Clinical Evaluation of Total IgE in Tears of Patients with Allergic Conjunctivitis Disease Using a Novel Application of the Immunochromatography Method
allergic conjunctivitis disease immunochromatography immunoglobulin E
2010/11/16
The positive ratio obtained by this novel application of the immunochromatography assay was 38 of the 41 in the patients with ACD and none in the 7 controls. IgE indices for the VKC group, AKC group a...
Local Induction of a Specific Th1 Immune Response by Allergen Linked Immunostimulatory DNA in the Nasal Explants of Ragweed-Allergic Subjects
allergen allergic rhinitis CpG motif immunotherapy vaccination
2010/11/16
RW or Amb-a-1 increased the number of IL-4, IL-5, and IL-13 mRNA+ cells in the tissue compared to medium alone. AIC had similar cytokine mRNA reactivity as control tissue. AIC and TT increased IFNγ-mR...
The Relationship between Asthma and Allergic Rhinitis in the Iraqi Population
allergen allergic rhinitis allergy asthma
2010/11/16
Background: Recently, extensive research has established that epidemiologic and therapeutic links exist between allergic rhinitis and asthma. The objective of this study was to clarify this associatio...
Changing Prevalence and Severity of Childhood Allergic Diseases in Kyoto, Japan, from 1996 to 2006
allergic disease epidemiology prevalence questionnaire schoolchildren
2010/11/16
Background: Published data regarding changes in the prevalence of childhood allergic diseases in Japan have been limited.
Methods: To observe changes in the recent trends of the childhood allergy epi...
Management of Food Allergy in Japan "Food Allergy Management Guideline 2008 (Revision from 2005) " and "Guidelines for the Treatment of Allergic Diseases in Schools"
anaphylaxis food allergy oral food challenge test referral relationship school
2010/11/16
In 2005, the "Food Allergy Management Guideline 2005" was published. In order to encompass food allergy from infancy to adulthood, the project committee included not only pediatricians, but also inter...