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Comparison of the Bronchodilative Effects of Salbutamol Delivered via Three Mesh Nebulizers in Children with Bronchial Asthma
asthma therapy lung function mesh nebulizer residual volume salbutamol
2010/11/16
Background: We compared the bronchodilative effects of salbutamol delivered via 3 different mesh nebulizers, Aeroneb-go®(AE), Omron-NE-U22®(OM) and Pari-eMotion®(PA).
Methods: We enrolled...
Pharmacokinetics of Beclomethasone Dipropionate in an Hydrofluoroalkane-134a Propellant System in Japanese Children with Bronchial Asthma
beclomethasone dipropionate children with bronchial asthma hydrofluoroalkane-134a Japanese pharmacokinetics
2010/11/19
The area under the concentration-time curve from time zero to the last quantifiable time (AUC0-t) was 1659 ± 850pg·h/mL (arithmetic mean ± standard deviation (SD)), the maximum concentration observed ...
Anti-endothelial cell IgE antibodies in children with bronchial asthma
anti-endothelial cell antibodies bronchial asthma IgE
2010/11/24
In the cellular ELISA, the IgE class of AECA was detected significantly more frequently in children with asthma (25/156; 16.0%) than in healthy controls (2/203; 1.0%; P > 0.01). There were no differen...
Population pharmacokinetics of pranlukast hydrate dry syrup in children with bronchial asthma
children with bronchial asthma population pharmacokinetics pranlukast
2010/11/24
Apparent clearance (CL/F) was 1.81 and 1.14 L/h per kg in children and adults, respectively. According to subgrouping of children, no significant difference was observed in CL/F between infants (3-6 y...
Urinary leukotriene E4 and 11-dehydro-thromboxane B2 excretion in children with bronchial asthma
bronchial asthma cysteinyl leukotrienes 11-dehydro-thromboxane B2 leukotriene E4 thromboxane A2
2010/11/22
Urinary LTE4 levels during an acute attack (median 476 pg/mg creatinine; range 191-1100 pg/mg creatinine) and during the stable condition (median 332 pg/mg creatinine; range 128-965 pg/mg creatinine) ...