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A Randomized Controlled Trial of Intravenous Magnesium Sulphate as an Adjunct to Standard Therapy in Acute Severe Asthma
Acute severe asthma Magnesium sulfate Treatment
2009/12/18
Though intravenous (IV) Magnesium Sulphate (MgS04) has additive effect to beta-2 agonists, its additive benefit in face of combination therapy with beta-2-agonists and ipratropium (standard therapy of...
Clinical Evaluation of Severe Asthma Attacks Requiring Tracheal Intubation and Mechanical Ventilation
bronchial asthma mechanical ventilation SABA smoking tracheal intubation
2010/11/16
Background: Although the number of patients requiring hospitalization due to asthma attacks has decreased over the years, there are many who still require hospitalization for tracheal intubation and m...
The E-selectin mediates the interaction of activated endothelial cells with leukocytes and plays a
fundamental role in the pathogenesis of asthma. It has been suggested that an S/R (Serine128Arginine...
Inhaled furosemide is not effective in severe asthma in children
asthma furosemide inhalation oxygen saturation peak expiratory flow
2010/11/25
The purpose of the present study was to determine whether or not inhaled furosemide has any therapeutic benefit in acute asthma in children. Aerosolized furosemide (20 mg) was administered four times ...
Effect of a leukotriene receptor antagonist, pranlukast hydrate, on airway inflammation and airway hyperresponsiveness in patients with moderate to severe asthma
airway hyperresponsiveness airway inflammation asthma eosinophils leukotriene leukotriene receptor antagonist
2010/11/25
Asthma is characterized by chronic airway inflammation and the recruitment of inflammatory cells, typically eosinophils and lymphocytes, into the airway. Although several chemical mediators are releas...
Treatment and management of severe asthma in childhood through to young adult patients: 12th Japanese Society of Allergology Meeting, Spring Clinical Meeting, Lecture of the Chairman
adolescence asthma death bronchial asthma epidemiology infantile asthma young adult
2010/11/25
Asthma treatments have changed radically due to elucidation of morbidity and development of medicine/treatment strategies. The Global Initiative for Asthma consists of a six-part asthma management pro...
Association of Tumor Necrosis Factor-α and Neutrophilic Inflammation in Severe Asthma
myeloperoxidase neutrophilic inflammation neutrophils severe asthma tumor necrosis factor-α
2010/11/22
The concentration of TNF-α was not correlated with neutrophils in healthy controls or mild asthma patients. In sputum from severe asthma patients, however, the concentration of TNF-α is significantly ...