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近日,基因治疗领域权威期刊《Human Gene Therapy》在线发表了我校生命科学学院医学遗传学研究中心梁德生课题组脊髓性肌肉萎缩症(spinal muscular atrophy, SMA)基因编辑治疗研究的最新成果。文章题为“Seamless genetic conversion ofSMN2 toSMN1 via CRISPR/Cpf1 and single-stranded olig...
Background: The hippocampus is a tiny nub in the mammalian brain that is involved in forming, organizing, and storing memories. Global cerebral ischemia (GCI) and reperfusion induced apoptosis lead to...
Background: Esophageal, stomach, and colorectal cancers are commonly lethal gastrointestinal tract (GIT) neoplasms, causing almost two million deaths worldwide each year. some environmental risk facto...
Background: Apolipoprotein E (APOE), which its ε4 allele has been reported as a risk factor in late onset Alzheimer’s disease (AD), is the main cholesterol carrier in the brain. ATP-binding cassette t...
The prostate is a small gland located below the bladder and upper part of the urethra. In developed countries prostate cancer is the second common cancer (after skin cancer), and also the second leadi...
Gene and Aging     Gene  Aging  Reactive oxygen species  Free radical       2009/12/7
Collection of multiple processes that increase the chronological age of an organism leading to death is defined as aging, and even though important, it is poorly understood. Recent research has shown ...
Background and the purpose of the study: Of the gene delivery systems, non-viral polycationic gene delivery nanosystems have been alternatively exploited as a relatively safe delivery reagents compare...
Background: Deletions of the DAZ (deleted in azoospermia) genes within the human Y chromosome's AZFc region are the most common cause of spermatogenesis failure. These deletions are usually assessed b...

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