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Preventative Effect of a Flavonoid, Enzymatically Modified Isoquercitrin on Ocular Symptoms of Japanese Cedar Pollinosis
diet therapy flavonoid Japanese cedar pollen pollinosis quercetin
2010/11/16
During the entire study period, ocular symptom + medication score for the EMIQ group was significantly lower (p < 0.05) than that of the placebo group. When limited to the period, ocular symptom score...
Effects of Pranlukast Hydrate on Airway Hyperresponsiveness in Non-Asthmatic Patients with Japanese Cedar Pollinosis
airway responsiveness allergic rhinitis leukotriene one airway-one disease pranlukast hydrate
2010/11/16
Background: Recent studies have suggested that allergic rhinitis is closely related to bronchial asthma, reflecting the "one airway-one disease" hypothesis. It is unclear if the effects of pranlukast,...
Allergic Potency of Japanese Cedar Pollen Cry j 1 Is Reduced by a Low Concentration of Hypochlorous Acid Generated by Electolysis
Cry j 1 human hypochlorous acid immunogenicity Japanese cedar pollinosis
2010/11/16
Background: Although Japanese cedar (Cryptomeria japonica) pollinosis has developed into a health problem, few methods eradicate indoor allergens completely. In a recent study, however, the effectiven...
Absence of Nasal Blockage in a Japanese Cedar Pollen-Induced Allergic Rhinitis Model Mouse
allergic rhinitis animal model cedar pollen nasal blockage sneezing
2010/11/16
The serum Cry j 1-specific IgE level showed clear elevation only in the group sensitized by Cry j 1 + Al(OH)3 and then challenged by Cry j 1. No elevations were seen in the groups sensitized by pollen...
A Clinical Study of Japanese Cedar (Cryptomeria japonica) Pollen-Induced Asthma
acethylcholine bronchial provocation test Japanese cedar non-specific airway hypersensitivity pollen-induced asthma
2010/11/17
Background: Grass and birch pollens are known to induce asthma. However there are few reports about other pollen-induced asthma. Japanese cedar is the most common allergen in rhinitis in Japan but is ...
Patterns of Drug Prescription for Japanese Cedar Pollinosis Using a Clinical Vignette Questionnaire
allergic rhinitis guideline Japan physician's practice patterns questionnaires
2010/11/17
Our investigation suggested that, compared to ENTs, GPs and IMs have a lower tendency to concomitantly prescribe drugs for localized treatment such as nasal corticosteroids and eye drops with oral med...
Enhanced Production of IgE Anti-Japanese Cedar Pollen Specific Antibodies by Peripheral Blood B Cells from Patients with Japanese Cedar Pollinosis
B cells class switching ELISA immobilized anti-CD3 Japanese cedar pollen
2010/11/17
Background: IgE antibodies against Japanese cedar pollen (JCP) play an important role for the pathogenesis of the cedar pollinosis, but the mechanism of their production has been unclear. We explored ...
Effect of Cry-consensus Peptide, a Novel Recombinant Peptide for Immunotherapy of Japanese Cedar Pollinosis, on an Experimental Allergic Rhinitis Model in B10.S Mice
allergic rhinitis Cry j 1 Cry j 2 Japanese cedar pollinosis T-cell epitope
2010/11/18
Cry-consensus peptide markedly inhibited Cry j 1-induced sneezes, eosinophil infiltration, and eosinophil peroxidase (EPO) activity in nasal tissue. Cry-consensus peptide inhibited the production of a...
Relationship between Airborne Cry j 1 and the Onset Time of the Symptoms of Japanese Cedar Pollinosis Patients
Cry j 1 electron spin resonance (ESR) radical immunoassay Japanese cedar (JC) pollinosis pollen information symptom score
2010/11/18
Background: Some patients with Japanese cedar (JC) pollinosis already show pollinosis symptoms before the first day of the pollen season as determined by microscopic pollen counts.
Methods: Airborne ...
Clinical Efficacy of Probiotic Bifidobacterium longum for the Treatment of Symptoms of Japanese Cedar Pollen Allergy in Subjects Evaluated in an Environmental Exposure Unit
Allergy Bifidobacterium environmental exposure unit (EEU) Japanese cedar pollinosis probiotic
2010/11/18
In comparison with placebo, BB536 intake significantly reduced the ocular symptom scores during JCP exposures. Evaluating delayed symptoms after exposures indicated that scores for disruption of norma...
Omalizumab is Effective and Safe in the Treatment of Japanese Cedar Pollen-induced Seasonal Allergic Rhinitis
anti-IgE antibody IgE omalizumab pollinosis seasonal allergic rhinitis (SAR)
2010/11/19
Primary and all secondary efficacy variable scores were significantly lower in the omalizumab group than in the placebo group (P < .01). Serum free IgE levels markedly decreased in the omalizumab grou...
Effect of Antihistamine Eye Drops on the Conjunctival Provocation Test with Japanese Cedar Pollen Allergen
allergen provocation test allergic conjunctivitis antihistamine eye drops Japanese cedar pollinosis ketotifen fumarate levocabastine hydrochloride
2010/11/19
Preadministration of antihistamine eye drops suppressed the symptoms induced by the allergen, which suggests that this is an effective early therapy for Japanese cedar pollinosis, if it is started bef...
Inhibition of the Antigen Provoked Nasal Reaction by Second-generation Antihistamines in Patients with Japanese Cedar Pollinosis
allergic rhinitis epinastine hydrochloride fexofenadine hydrochloride nasal provocation rhinoscopy
2010/11/19
Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan. The purpose of this study w...
Effect of modified immunotherapy with an allergen-pullulan conjugate in patients with Japanese cedar pollinosis
eosinophil immunotherapy Japanese cedar pollinossis mast cell seasonal allergic rhinitis Th1 cytokine Th2 cytokine
2010/11/25
Immunologic mechanisms of allergen immunotherapy are still incompletely understood. Immunotherapy of a higher maximum tolerance dose with reduced risks of systemic reactions, such as anaphylaxis, need...
Japanese cedar pollen in floating indoor house dust after a pollinating season
highly sensitive Cry j1 assay house dust Japanese cedar pollen Japanese cedar pollinosis self-care
2010/11/22
The results showed that, indoors, a lot of Japanese cedar pollen (JCP) was found on the floor (tatami mats, carpets), sofas and curtains. The number of JCP in living rooms peaked in April after the po...