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Oral Administration of Heat-Killed& Lactobacillus gasseri OLL2809 Reduces Cedar Pollen Antigen-Induced Peritoneal Eosinophilia in Mice
eosinophil Lactobacillus gasseri probiotics Th1/Th2 balance
2010/11/17
We demonstrated that the oral administration of heat-killed L. gasseri OLL2809 suppresses eosinophilia via the modulation of Th1/Th2 balance. These observations suggested that heat-killed L. gasseri O...
Increased Number of CCR4-positive Cells in the Duodenum of Ovalbumin-induced Food Allergy Model NC/jic Mice and Antiallergic Activity of Fructooligosaccharides
antiallergic activity CCR4- and CCR5-positive cells food allergy fructooligosaccharides prebiotic food
2010/11/18
The number of CCR4-positive cells increased significantly in Group 2 as compared with Group 1 and tended to decrease in Group 3 as compared with Group 2. Relatively few CCR5-positive cells were observ...
Effect of Oral Administration of CpG ODN-OVA on WBB6F1-W/Wv Mice
allergy CpG motif oral-sensitization ovalbumin WBB6F1-W/Wv mice
2010/11/18
The antigen-specific IgG1 antibody titer in the CpG ODN-OVA-sensitized W/Wv mice was lower than in the OVA-sensitized group, but the IgG2a titer was higher. ASA was not induced by i.p. OVA challenge. ...
Reduced Serum Antibody Production and Acute Airway Inflammation in Interleukin 6-deficient Mice Challenged with Ovalbumin
animal asthma cytokine eosinophil IL-6
2010/11/19
Background: IL-6 is a unique cytokine that has pro- and anti-inflammatory property. The purpose of this study was to clarify the role of IL-6 in the allergic airway inflammation.
Methods: We challeng...