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Prevention of seminiferous tubular atrophy in a naturally cryptorchid rat model by early surgical intervention
Cryptorchidism orchiopexy testis descent
2009/2/17
In an attempt to determine whether the seminiferous tubular atrophy of the cryptorchid testis is preventable by early surgical correction of the cryptorchid state, aberrantly developed gubernacula d...
2,5-hexanedione exposure in the rat results in long-term testicular atrophy despite the presence of residual spermatogonia
Germ cell repopulation Sertoli cell toxicity spermatogonia
2009/2/7
Charles River CD rats (approximate weight, 208 g) were exposed to 1.0% 2,5-hexanedione (2,5-HD) in drinking water for 5 weeks. Rats were killed 27, 60, and 75 weeks after exposure to evaluate the re...