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Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity
Human spermatozoa liquid peroxidation superoxide production hydrogen peroxide production
2009/2/23
Spontaneous lipid peroxidation in washed human spermatozoa was induced by aerobic incubation at 32 C and measured by malonaldehyde production; loss of motility during the incubation was determined s...
Alpha-glucosidase as a specific epididymal enzyme marker. Its validity for the etiologic diagnosis of azoospermia
azoospermia epididymal marker aglucosidase carnitine obstructive pathology
2009/2/23
Azoospermic semen was obtained from 39 vasectomized men and 93 patients consulting for infertility. The latter underwent bioclinical investigations including measurement of plasma FSH and testicular...
Occurrence of DOPA/5-HTP Decarboxylase in Human Seminal Plasma：Kinetic Parameters and Demonstration of a Naturally Occurring Inhibitor of the Enzyme
DOPA/5-HTP decarboxylase human seminal plasma biogenic amines
2009/2/18
The authors found that DOPA/5-HTP decarboxylase was present in the human seminal plasma and that its activity was lower in fertile men than in infertile men. The Km and Vmax of the enzyme were, re...
Release of angiotensin-converting enzyme（ACE）from human spermatozoa during capacitation and acrosome reaction
ACE content ejaculate kininase II
2009/2/13
The present study examines the release of angiotensin-converting enzyme (ACE) from human spermatozoa during capacitation conditions and in correlation to acrosome reaction and cell death. The ACE ...
Lipid peroxidation and antioxidant enzyme activities in the rat testis after cigarette smoke inhalation or administration of polychlorinated biphenyls or polychlorinated naphthalenes
Reactive oxygen oxidative stress superoxide dismutase catalase cigarette smoking environmental chemicals
2009/2/12
Lipid peroxidation products and antioxidant enzyme activities were studied in the rat testis following exposures to cigarette smoke, polychlorinated biphenyls (PCBs), or polychlorinated naphthalen...
Comparison of effects of 0.5 and 3.0 Gy X-irradiation on lipid peroxidation and antioxidant enzyme function in rat testis and liver
0.5 and 3.0 Gy X-irradiation lipid peroxidation antioxidant enzyme function rat testis
2009/2/12
The prooxidant effect of X-irradiation on rat testis and liver tissue was studied with doses of 0.5 and 3.0 Gy; the latter dose kills the proliferating spermatogonia and causes a maturation-depletio...
Antioxidant enzyme activity in the maturing rat testis
Antioxidant enzyme activity maturing rat testis
2009/2/11
Developmental profiles of the activity of the antioxidant enzymes superoxide dismutase (SOD), catalase, glutathione peroxidase (GSH-Px), glutathione transferase (GSH-Tr), and hexose monophosphate ...
Overview of enzyme inhibitors and anti-androgens in prostatic cancer
enzyme inhibitors anti-androgens prostatic cancer
2009/2/7
Surgical castration and estrogen therapy for prostate cancer were developed in 1941, and have been shown to improve both quality of life and survival. Little change in the therapeutics of prostate...
Susceptibility of glycolytic enzyme activity and motility of spermatozoa from rat, mouse, and human to inhibition by proven and putative chlorinated antifertility compounds in vitro
glycolytic enzyme activity motility spermatozoa rat mouse human inhibition
2008/12/26
Nonhormonal contraceptives that act by blocking energy metabolism within sperm have the advantage over spermatogenic inhibitors by their fast onset of infertility and their almost immediate restorat...
Leydig cell aging：steroidogenic acute regulatory protein（StAR）and cholesterol side-chain cleavage enzyme
Leydig cell aging protein（StAR） cholesterol side-chain cleavage enzyme
2008/12/26
Primary points of control in steroidogenesis are the transport of cholesterol from intracellular stores to the inner mitochondrial membrane, and the subsequent conversion of cholesterol to pregnenolon...
Recombinant Adenovirus Mediated Prostate-Specific Enzyme Pro-Drug Gene Therapy Regulated by Prostate-Specific Membrane Antigen（PSMA）Enhancer/Promoter
Cytosine deaminase prostate adenocarcinoma
2008/12/24
Gene directed enzyme pro-drug therapy (GDEPT) is one of the adjuvant therapeutic regimens for advanced prostate adenocarcinoma, and this research intended to explore how to apply targeting therapy o...
Temporal Relationships Among Testosterone Production, Steroidogenic Acute Regulatory Protein (StAR), and P450 Side-Chain Cleavage Enzyme（P450scc）During Leydig Cell Aging
Leydig cell cyclic AMP steroidogenesis Brown Norway rat
2008/12/22
Previous studies have shown that the capacity of Leydig cells from aged (21-24-month-old) Brown Norway rats to produce testosterone is reduced from young (4-month-old) levels, and that this is cor...