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Tubular Krukenberg tumor with an occult primary can cause problems in histopathologic diagnosis, by mimicking primary ovarian tumors. We present one such occurrence in a 32year old female who underwen...
The effect of tumor necrosis factor on human sperm motility in vitro
tumor necrosis factor human sperm motility
2009/2/23
Tumor necrosis factor (TNF alpha) is present in elevated levels in peritoneal fluid from infertile women with endometriosis. The effect of TNF alpha on human sperm motility in vitro was evaluated ...
Virilizing Testicular Tumor:In Vivo Studies of Steroid Secretion
in vivo studies of steroid secretion virilizing testicular tumor testicular tumor steroid secretion
2009/2/19
Findings in a six-year-old boy with a virilizing tumor of the left testis are presented. His bone age was 14 years. Serum testosterone (5.9 ng/ml), urinary 17-ketosteroid (29 mg/24 hr), and pregnane...
Atrial natriuretic factor inhibits the phosphorylation of protein kinase C in plasma membrane preparations of cultured Leydig tumor cells
Atrial natriuretic factor protein kinase C Leydig tumor cells cGMP plasma membranes
2009/2/12
The peptide hormone atrial natriuretic factor (ANF) exerts its effect in a receptor-mediated fashion and the membrane-bound form of guanylate cyclase represents a biologically active ANF receptor;...
Direct and indirect effects of murine interleukin-2, gamma interferon, and tumor necrosis factor on testosterone synthesis in mouse Leydig cells
murine interleukin-2 gamma interferon tumor necrosis factor testosterone synthesis
2009/2/11
It was recently observed that treatment of patients with a high dosage of human interleukin (IL-2) resulted in suppression of plasma concentrations of testosterone. A murine model was developed to a...
The lack of effect of tumor necrosis factor-alpha, interleukin-1-alpha, and interferon-gamma on human sperm motility in vitro
Tumor necrosis factor interleukin-1 interferon human sperm motility
2009/2/10
Whether cytokines present in human peritoneal fluid reduce sperm motility, and thus contribute to infertility, is investigated. The human recombinant cytokines, tumor necrosis factor-alpha, interl...
Rat tumor Leydig cells as a test system for the study of Sertoli cell factors that stimulate steroidogenesis
Insulin-like growth factor I (IGF-l) paracrine factors
2009/2/7
Transplantable rat Leydig cell tumor H-540 was used to study the interactions between Leydig and Sertoli cells. These tumor cells maintain their steroidogenic capacity when cultured. Their responsiv...
Tumor necrosis factor and interleukin-1 stimulate testosterone secretion in adult male rat Leydig cells in vitro
umor necrosis factor interleukin-1 testis testosterone
2009/2/6
The actions of two cytokines, tumor necrosis factor (TNF) and interleukin-1 (IL-1), on testosterone production by dispersed adult testis cells and purified Leydig cells in culture were studied. In o...
Elevated levels of inhibin-A and immunoreactive inhibin in aged male Wistar rats with testicular Leydig cell tumor
Testis gonadotropins
2008/12/29
This study was undertaken to investigate the endocrine changes that occur in male Tig:Wistar rats with Leydig cell tumors, with special reference to immunoreactive inhibin (ir-inhibin) and its dimer...
Cordyceps sinensis and its fractions stimulate MA-10 mouse Leydig tumor cell steroidogenesis
Human chorionic gonadotropin steroidogenic acute
2008/12/29
The effects of Cordyceps sinensis (CS) and its extracted fractions on steroidogenesis in MA-10 cells were determined. Different concentrations of CS and 3 fractions of CS (F1, a water-soluble polysa...
The effect of cardiac arrest on the blood-testis barrier to albumin, tumor necrosis factor-alpha, pituitary adenylate cyclase activating polypeptide, sucrose, and verapamil in the mouse
blood-testis albumin tumor necrosis factor-alpha pituitary adenylate cyclase
2008/12/26
Impotence commonly occurs after events such as acute myocardial infarction, coronary bypass, head trauma, and cerebral bleeding, including subarachnoid hemorrhage. We hypothesize that the hypoxia ac...
Receptor Isoform and Ligand-Specific Modulation of Dihydrotestosterone-Induced Prostate Specific Antigen Gene Expression and Prostate Tumor Cell Growth by Estrogens
Androgen receptor androgens estrogen receptor
2008/12/23
Androgens via the androgen receptor (AR) play crucial roles in prostate physiology and pathophysiology. These androgen actions can be either inhibited or potentiated by estrogens. The mechanisms of ...
Gene and Protein Profiling of the Response of MA-10 Leydig Tumor Cells to Human Chorionic Gonadotropin
Testis, gene ontology genomics proteomics steroidogenesis
2008/12/22
Activation of the steroidogenic machinery by peptide hormones involves a number of steps for transmitting signals from the plasma membrane to mitochondria in a spatially and temporally coordinated...
Feasibility of Simultaneous Testicular Microdissection for Sperm Retrieval and Ipsilateral Testicular Tumor Resection in Azoospermic Men
Feasibility of Simultaneous Testicular Microdissection Sperm Retrieval Ipsilateral Testicular Tumor Resection Azoospermic Men
2008/12/22
Male infertility is known to be associated with testicular tumors (Honig et al, 1994). In one recent report (Nobert and Goldstein, 2001), at least a 16-fold increase in the risk of testicular cancer, ...
Primary Carcinoid Tumor of the Testis Found at the Time of Elective Sterilization
Primary Carcinoid Tumor Testis Elective Sterilization
2008/12/22
Carcinoid tumor of the testis can occur as a primary neoplasm or as metastases. This tumor accounts for less than 1% of all testicular neoplasms, with 1.1%–3.1% of cases associated with carcinoid ...