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Reversibility of long-term effects of GnRH agonist administration on testicular histology and sperm production in the nonhuman primate
GnRH agonist LH testosterone testis morphology electron microscopy monkeys
2009/2/23
The present investigation evaluates the long-term effects of GnRH agonist treatment on testicular histology, sperm production and the subsequent recovery of these parameters. Four adult rhesus monke...
Effects of an LHRH agonist analog upon sexual function in male dogs. Suppression, reversibility, and effect of testosterone replacement
LHRH agonists D-Na!(2)6-LHRH spermatogenesis
2009/2/20
Male beagle dogs were injected once daily with 10 micrograms/kg of [6-D-(2-naphthyl)alanine]-LHRH (D-Nal(2)6-LHRH), a potent LHRH agonist, for periods up to 42 days, with recovery periods up to 172 ...
Further Studies on the Inhibitory Effect of [D-A1a6, des-Gly-NH210]LHRH Ethylamide on Spermatogenesis and Steroidogenesis in the Rat：Reversibility and Effect of Androgen Administration
antifertility spermatogenesis LHRH agonist
2009/2/18
Following the recent observation that chronic treatment with [D-Ala6, des-Gly-NH210]LHRH ethylamide, a potent LHRH agonist, leads to an almost complete degeneration of seminiferous tubules in the ra...