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In vivo model for chronic direct intratesticular drug administration
Male infertility testicular toxicity miniosmotic pumps
2009/2/12
The efficacy and toxicity of a new method for chronic direct intratesticular drug infusion were assessed in a rat model. To this end, luteinizing hormone (LH) or buffer was infused via miniosmotic...
Intracavernosal pressure monitoring in mice：responses to electrical stimulation of the cavernous nerve and to intracavernosal drug administration
Intracavernosal pressure monitoring mice electrical stimulation intracavernosal drug administration
2008/12/25
With the development of transgenic mice to evaluate mechanisms of erectile function, it appears particularly advantageous to develop a standardized mouse model of penile erection. The purpose of the...
Transdermal electromotive multi-drug administration for Peyronie's disease：preliminary results
Transdermal electromotive multi-drug administration Peyronie's disease preliminary results
2008/12/25
The purpose of this study was to clarify the actual therapeutic potential of a new transdermal drug delivery system (electromotive drug administration; EMDA) for selected patients with Peyronie's ...
Recombinant Adenovirus Mediated Prostate-Specific Enzyme Pro-Drug Gene Therapy Regulated by Prostate-Specific Membrane Antigen（PSMA）Enhancer/Promoter
Cytosine deaminase prostate adenocarcinoma
2008/12/24
Gene directed enzyme pro-drug therapy (GDEPT) is one of the adjuvant therapeutic regimens for advanced prostate adenocarcinoma, and this research intended to explore how to apply targeting therapy o...
Drug-Metabolizing Enzymes and Transporters：Expression in the Human Prostate and Roles in Prostate Drug Disposition
Drug-Metabolizing Enzymes Transporters Human Prostate Prostate Drug Disposition
2008/12/23
Local biotransformation enzymes and transporter proteins in tissues may exert a profound effect on drug pharmacokinetics in those tissues. Thus, the use of drugs for the treatment of benign prostatic ...
A Short Course on the Food and Drug Administration: What You Should Know
Short Course Food Drug Administration
2008/12/15
US government bureaucracy and regulatory agencies are thought of as pits of deep mystery to most scientists, but the regulatory issues are built on codes and precedent. The Food and Drug Administratio...
Food and Drug Administration Approves Contraceptive for Continuous Use
Contraceptive pregnancy
2007/5/24
May 22, 2007，The Food and Drug Administration (FDA) today approved Lybrel, the first continuous use drug product for prevention of pregnancy.