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肿瘤医院放射治疗科李晔雄教授领导的NK/T细胞淋巴瘤全国多中心协作组开展的结外鼻型NK/T细胞淋巴瘤列线图(Nomogram)研究日前在世界顶尖级肿瘤杂志《Leukemia》发表(2014年IF 10.43)。这一研究在国际上首次提出了结外鼻型NK/T细胞淋巴瘤的列线图模型,该模型可对治疗前患者进行疾病风险评分,并预估患者5年总生存率。该模型的建立可为后续基于风险分层的治疗决策提供依据。
Inhibition of Leukemia Cell Proliferation using c-myb Antisense Oligonucleotides
Gene therapy antisense oligonucleotides c-myb leukemia
2009/6/25
Antisense oligodeoxynucleotides (AS-ODNs) are short DNA sequences synthesized complementary to the mRNA and they inhibit the expression of the target gene by forming a mRNA-DNA duplex. This strategy c...