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Aims: Chronic hepatitis C virus (HCV) infection is often associated with glucose metabolic disorders and iron overload. It has recently been shown that reactive oxygen species (ROS) increase gluconeog...
Insulin resistance (IR) is recognized to be of critical importance in a variety of metabolic diseases and coronary artery disease (CAD). Impaired skeletal muscle glucose utilization (SMGU) plays an im...
Objective: The aims of this study were to examine the relationships between adiponectin, insulin, visfatin and weight at birth in healthy term infants. Design and methods: Anthropometric parameters in...
Metabolic syndrome is strongly associated with insulin resistance and consists of a constellation of factors such as hypertension and hyperlipidemia that raise the risk for cardiovascular diseases and...
In recent years, some metal ions and their complexes have been found to treat diabetes mellitus (DM) in not only experimental animals but also humans. Among them, vanadyl(IV) and zinc(II) ions as well...
We synthesized a 1 : 2 complex between the vanadyl(IV)or vanadate(V)ion and benzohydroxamic acid (BHA), and assessed their insulin-like activity in terms of the inhibitory effects on free fatty acid r...
Five kinds of N-substituted 3-hydroxy-2-methyl-4(1H)-pyridinones, and three kinds of 1-hydroxy-2(1H)-pyrimidinones were synthesized. Treatment of 3-hydroxy-4(1H)-pyridinones with VO(acac)2 in CH3OH ex...
Tasting sweet food elicits insulin release prior to increasing plasma glucose levels, known as cephalic phase insulin release (CPIR). The characteristic of CPIR is that plasma insulin secretion occu...
The exocyst is an octameric complex involved in docking or tethering of secretory vesicles to fusion sites of the plasma membrane. Sec6 is the core subunit of the exocyst complex. Here we identify an ...

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