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Identification of material parameters based on Mohr-Coulomb failure criterion for bisphosphonate treated canine vertebral cancellous bone
material parameter identification Mohr-Coulomb failure criterion trabecular bone
2014/12/4
Nanoindentation has been widely used to study bone tissue mechanical properties. The common method and equations for analyzing nanoindentation, developed by Oliver and Pharr, are based on the assumpti...
Effects of 1 to 3 years' treatment with alendronate on mechanical properties of the femoral shaft in a canine model: implications for subtrochanteric femoral fracture risk
subtrochanteric fractures femur bisphosphonates
2014/12/4
Bisphosphonate (BP) treatment used to prevent bone loss in postmenopausal osteoporosis has recently been implicated in an apparent increase in subtrochanteric femoral fractures. Previous work showed t...
Effects of suppression of bone turnover on cortical and trabecular load sharing in the canine vertebral body
trabecular bone cortical shell suppressed bone turnover
2014/12/4
The relative biomechanical effects of antiresorptive treatment on cortical thickness vs. trabecular bone microarchitecture in the spine are not well understood. To address this, T-10 vertebral bodies ...
A computational assessment of the independent contribution of changes in canine trabecular bone volume fraction and microarchitecture to increased bone strength with suppression of bone turnover
trabecular bone bone strength suppressed bone turnover
2014/12/4
This study addressed the effects of changes in trabecular microarchitecture induced by suppressed bone turnover—including changes to the remodeling space—on the trabecular bone strength–volume fractio...
Theoretical analysis of alendronate and risedronate effects on canine vertebral remodeling and microdamage
bisphosphonate bone remodeling
2014/12/4
Bisphosphonates suppress bone remodeling activity, increase bone volume, and significantly reduce fracture risk in individuals with osteoporosis and other metabolic bone diseases. The objectives of th...
Bisphosphonate Treatment Modifies Canine Bone Mineral and Matrix Properties and their Heterogeneity
bisphosphonates bone remodeling
2014/12/4
Bone loss and alterations in bone quality are major causes leading to bone fragility in postmenopausal women. Although bisphosphonates are well known to reduce bone turnover and prevent bone loss in p...
In Vitro Characterization of Docetaxel as a Radiosensitizer in Canine and Feline Cancer Cell Lines
Docetaxel Chemotherapy Radiation Therapy In Vitro
2013/2/19
An In Vitro study was conducted to investigate docetaxel as a radiation sensitizer in four canine (mammary carcinoma—CMT12 and CMT25, osteosarcoma—OS2.4, and transitional cell carcinoma—PTCC), and one...
Canine Cutaneous Mast Cell Tumor: Biologic Behavior and Its Correlation with Prognostic Indicators
Sabrina dos Santos Costa Poggiani Erika Maria Terra
2013/2/19
Cutaneous mast cell tumor (MCT) shows a variable biological behavior in dogs and may present either as solitary masse that can be treated and cured with surgical removal or as a systemic metastatic an...
Evaluation of Collection and Distribution of Samples for Histological, Stereological Analysis and Cell Culture of Canine Mast Cell Tumors
Mast Cell Tumor Oncologic Surgery Canine Tumor Collection Stereological Analysis
2013/2/19
Objective: To collect high quality, representative tissue material from tumors and manage its distribution to different laboratories. Design: Prospective controlled study. Animals: Thirty-six dogs wit...
Localization of the VP2 Protein of Canine Parvovirus Type 2 on the Baculovirus Envelop and Its Immunogenicity in a Mouse Model
Canine Parvovirus Type 2 VP2 Protein Baculovirus gp64 TM and CTD Subunit Vaccine
2013/2/19
In this study, the full-length VP2 gene of canine parvovirus type 2 (CPV-2) was cloned into the pBacSC vector which possesses baculovirus transmembrane domain (gp64 TM) gene, baculovirus cytoplasmic d...
Immunoexpression of Cathepsin D and S100A4 Protein and Their Molecular Subtyptes in Canine Mammary Carcinomas
Cathepsin Mammary Tumors Metastasis-Associated Proteins Molecular Subtypes S100 Protein
2013/2/19
Cathepsin D (CD), a lysosomal protease, and S100A4 protein, a calcium binding motif, are considered to be involved in metastasis in various human cancers. No data regarding such proteins are available...
Canine Prostate Carcinoma: Four Clinical Cases in Sexually Intact and Neutered Dogs
Prostate Carcinoma Neutered Dog
2013/2/19
Prostate cancer is one of the most important malignancies in men. In old men the frequency of prostate cancer at necroscopy has been reported to exceed 40%. Dogs are the only large mammals other than ...
Comparison of canine retraction using slide friction less ligature modules with conventional modules - an in vivo study
slide friction ligature modules conventional modules
2010/11/3
Comparison of canine retraction using slide friction less ligature modules with conventional modules - an in vivo study.
A new method for rapid Canine retraction
Canine retraction Distraction osteogenesis method rapid bone formation
2009/12/24
Distraction osteogenesis method (Do) in bone lengthening and rapid midpalatal expansion have shown the great ability of osteognic tissues for rapid bone formation under distraction force and special p...
Multi-body simulation of a canine hind limb: model development,experimental validation and calculation of ground reaction forces
Multi-body simulation a canine hind limb ground reaction forces
2010/2/25
In conclusion, it could be demonstrated that the developed MBS-model is suitable for simulating ground reaction forces of dogs during walking. In forthcoming investigations the model will be developed...