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王晓晖教授团队在《CNS Neuroscience & Therapeutics》发文:揭示D-Ser2-Oxyntomodulin改善Aβ31-35所致小鼠昼夜节律紊乱的作用及GLP-1受体机制(图)
山西医科大学 基础医学院 王晓晖教授
2023/12/21
近日,山西医科大学基础医学院病理教研室王晓晖教授团队在神经科学国际期刊《CNS Neuroscience & Therapeutics》杂志发表了最新研究成果:D-Ser2-oxyntomodulin ameliorated Aβ31-35-induced circadian rhythm disorder in mice.
Two groups of divers (Group A and B) were compressed to 500 msw with trimix (n = 3) and heliox (n = 3). After 4 d at saturation depth Group A had a gas change to heliox. Both groups were followed with...
CNS oxygen toxicity in the rat: role of ambient illumination
hyperbaric CNS oxygen toxicity Central Nervous System animal rat
2009/7/14
The effect of ambient illumination on sensitivity to CNS oxygen toxicity was studied in awake male rats. Continuous recording of the EEG was obtained with chronically implanted cortical electrodes. Th...
CNS oxygen toxicity in oxygen-inert gas mixtures
oxygen toxicity nitrogen hyperbaric animal rat
2009/7/14
Central nervous system oxygen toxicity in hyperbaric oxygen-inert gas mixtures was studied by exposing male rats to various gas mixtures having the same oxygen partial pressure and varying pressures o...
Visual reaction time performance preceding CNS oxygen toxicity
human oxygen toxicity visual
2009/7/14
The visual reaction time performance of divers experiencing CNS oxygen toxicity was assessed during the development of closed-circuit 100percent oxygen breathing diving schedules at the U.S. Navy Expe...
Experimental determination of latency, severity, and outcome in CNS decompression sickness
decompression sickness neurological outcomes animal dog
2009/7/10
Twenty-eight dogs underwent a 300 fsw chamber dive designed to generate spinal cord decompression sickness (DCS), which was detected by observing a reduction in the amplitude of the spinal somatosenso...
CNS oxygen toxicity
Central Nervous System Diseases oxygen Hyperbaric Oxygenation adverse effects human
2009/6/4
This short manuscript will briefly present our current knowledge about CNS oxygen toxicity: the clinical manifestations, descriptions and incidence of symptoms, and the time – duration relationship th...
CNS manifestations of HPNS:revisited
High Pressure Neurological Syndrome HPNSpathophysiology Thermodynamic corticohippocampal synaptic activity frequency cognitive memory Central Nervous System
2009/6/2
Exposure to high pressures (HP) has been associated with the development of the high pressure neurological syndrome (HPNS) in deep-divers and experimental animals. In contrast, many diving mammals are...
Adult Neural Stem Cells:Redefining the Physio- and Pathology of the CNS
neurogenesis stem cells pharmacology development plasticity regeneration
2009/4/29
Stem cells are the “building blocks” of the body; they are self-renewing undifferentiated cells that give rise to the specialized cells of the tissues. In adult, stem cells are multipotent, they contr...
Magnesium sulfate suppresses electroencephalographic manifestations of CNS oxygen toxicity
oxygen toxicity seizure hyperbaric magnesium sulfate animalrat
2009/3/26
We studied the effects of parenteral magnesium sulfate (MgSO4) administration on electroencephalographic seizures induced by hyperbaric oxygen (HBO) in awake rats. Sixteen rats chronically implanted ...
Statistical approach to the analysis of sensitivity to CNS oxygen toxicity in rats
oxygen toxicity animal rat hyperbaric central nervous system
2009/3/25
Animal models are widely used for the study of CNS oxygen toxicity, but confusion still exists regarding the proper statistical approach to the analysis of the data. This paper is based on data collec...
Application of Several Multimedia Approaches to the Teaching of CNS Pharmacology: Parkinson’s Disease and Antiparkinsonism Drugs
Application Several Multimedia Approaches Teaching CNS Pharmacology Parkinson Disease Antiparkinsonism Drugs
2016/3/11
Computer and multimedia-based technologies have been incorporated into a course in Central Nervous System Pathology and Pharmacology in order to facilitate learning in this area and to address multipl...