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分析同时伴有2种及2种以上的荧光原位杂交(FISH)结果异常的多发性骨髓瘤(MM)患者的预后情况,筛选预后较差的MM者。 方法:共计纳入2011年7月至2017年2月期间767例在长征医院就诊的初诊MM患者,所有患者初诊时均进行FISH检测,所检测的FISH异常包括IgH易位、t(4;14)、t(11;14)、t(14;16)、17p-、1q扩增、-13/13q-,分析所有FISH异常对预后的影响...
观察脱落细胞学检查(EC)、荧光原位杂交技术(FISH)及膀胱肿瘤抗原(BTA)3种方法联合诊断肾盂癌的临床价值。方法回顾性分析保定市第二医院泌尿外科120例疑似肾盂癌患者临床病历资料,记录所有患者EC、FISH及BTA结果,以病理活检结果为金标准,分析单一或联合采用3种检查方法诊断肾盂癌的准确性,并绘制受试者工作曲线(ROC),比较单一或联合采用3种检查方法的价值。
Beginning in the late 1960s, landmark epidemiologic observations made in fish-eating populations from Greenland, Canada, Alaska, China, and Japan suggested an inverse association between the consumpti...
Beginning in the late 1960s, landmark epidemiologic observations made in fish-eating populations from Greenland, Canada, Alaska, China, and Japan suggested an inverse association between the consumpti...
Background: Parenteral fish-oil (FO) therapy is a safe and effective treatment for intestinal failure–associated liver disease (IFALD). Patients whose cholestasis does not resolve with FO may progress...
The steps in the development of important medical discoveries rest first on intuition and then on associations of a certain factor with a disease, followed by scientifically designed experiments. T...
Obesity in hypertensive patients is associated with dyslipidemia and insulin resistance, both of which are improved by weight control. n23 Fatty acids have diverse effects on mechanisms underlying ...
Although several studies have investigated the relation between fish consumption and the risk of cardiovascular diseases, less attention has been paid to the relation between fish consumption and c...
Histamine food poisoning is found to be associated with consumption of scombroid fish containing unusually high levels of histamine. Fish belonging to non-scombroid group may also cause histamine pois...
Omega-3 fatty acids (n-3) has shown to improve neuromotor function. This study examined the effects of docosahexaenoic acid (DHA) on complex reaction time, precision and efficiency, in female elite so...
Background: Fish is a rich source of n–3 polyunsaturated fatty acids (PUFAs) but also contains the neurotoxicant methyl mercury (MeHg). PUFAs may modify the relation between prenatal MeHg exposure and...
Background: Despite mechanistic data that linked fish and omega-3 (n–3) PUFAs with lower risk of chronic obstructive pulmonary disease (COPD), epidemiologic data remain scarce. Fish and n–3 PUFAs are ...
Background: Despite mechanistic data that linked fish and omega-3 (n–3) PUFAs with lower risk of chronic obstructive pulmonary disease (COPD), epidemiologic data remain scarce. Fish and n–3 PUFAs are ...
探讨荧光原位杂交(FISH)技术联合常规细胞遗传学检测骨髓增生异常综合征(MDS)患者染色体异常的临床价值。方法:运用FISH技术联合常规细胞遗传学检测100例经骨髓常规涂片及骨髓活检确诊的MDS患者的染色体异常情况,并对此100例患者进行随访。结果:100例MDS患者中FISH检测出48例有染色体异常,总异常检出率为48%,其中-5/5q-检出率最高,为16%,其余异常阳性检出率依次为20q-(...
探讨荧光原位杂交(FISH)技术在快速诊断早期自然流产绒毛染色体数目异常的临床应用价值。方法 应用FISH技术快速检测607例早期自然流产绒毛13、16、18、21、22号和X、Y染色体数目。结果 607例早期自然流产绒毛中,253例FISH检测出现异常信号,异常率为41.68%,其中15例13-三体、64例16-三体、3例18-三体、17例21-三体、3例21单体、35例22-三体、50例X单体...

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