搜索结果: 1-15 共查到“知识库 口腔医学 bone”相关记录131条 . 查询时间(0.238 秒)
Nmp4/CIZ suppresses the response of bone to anabolic parathyroid hormone by regulating both osteoblasts and osteoclasts
c-fos Fra-2 osteoclastogenesis
2014/11/6
How parathyroid hormone (PTH) increases bone mass is unclear, but understanding this phenomenon is significant to the improvement of osteoporosis therapy. Nmp4/CIZ is a nucleocytoplasmic shuttling tra...
High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/11/6
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad
autocrine signaling bone marrow cells breast cancer
2014/11/6
Breast cancer metastasis to bone triggers a vicious cycle of tumor growth linked to osteolysis. Breast cancer cells and osteoblasts express the epidermal growth factor receptor (EGFR) and produce ErbB...
Sonic hedgehog gene-enhanced tissue engineering for bone regeneration
sonic hedgehog gene-enhanced bone regeneration
2014/11/6
Improved methods of bone regeneration are needed in the craniofacial rehabilitation of patients with significant bone deficits secondary to tumor resection, congenital deformities, and prior to prosth...
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice
podosome organization bone density osteoclast functions
2014/11/6
The protein tyrosine kinase Pyk2 is highly expressed in osteoclasts, where it is primarily localized in podosomes. Deletion of Pyk2 in mice leads to mild osteopetrosis due to impairment in osteoclast ...
Reconstruction of mandibular defect with free fibular bone graft - A case report
Reconstruction of mandibular defect fibular bone graft
2010/11/3
Reconstruction of mandibular defect with free fibular bone graft - A case report.
Effects of α-DT cement with hydroxypropyl cellulose on bone augmentation within a titanium cap in the rabbit calvarium
Guided bone regeneration Bone grafts Histology
2010/11/26
The present study was performed to evaluate the effects of calcium phosphate cement (α-DT cement) containing α-TCP, dicalcium phosphate anhydrous, and tetracalcium phosphate mixed with hydroxypropyl c...
Histologic evaluation of the effect of nicotine administration on bone regeneration:a study in dogs
Smoking Nicotine Tobacco Bone regeneration
2009/10/20
The objective of this study was to investigate the histometric impact of nicotine on bone regeneration of surgically created alveolar ridge defects in dogs. Sixteen mongrel dogs were used. One defect ...
The current study aims to evaluate the new bone formation in polyvinylpyrrolidone (PVP) grafts inserted into the tibia of ten female rabbits. The animals were submitted to oophorectomy in order to ind...
Selective COX-2 inhibitor reduces bone healing in bone defects
Anti-inflammatory agents,non-steroidal Cyclooxygenase inhibitors Wound healing Rats
2009/10/20
Anti-inflammatory agents have been reported to regulate bone healing. The aim of this study was to investigate the effect of a selective cyclooxygenase-2 inhibitor (meloxicam) on bone healing in calva...
The influence of cigarette smoke inhalation on bone density:a radiographic study in rats
Smoking Bone density Rats Wistar
2009/10/19
The aim of this study was to evaluate the influence of cigarette smoke inhalation (CSI) and its cessation on tibiae bone quality. Forty-one male Wistar rats were randomly assigned to one of the follow...
Selective cyclooxygenase-2 inhibition prevents bone resorption
Alveolar bone loss Anti-inflammatory agents,non-steroidal Cyclooxygenase inhibitors Periodontitis Radiography dental
2009/10/19
The aim of the present work was to evaluate the effect of a selective cyclooxygenase-2 (COX-2) inhibitor (meloxicam) on the alveolar bone loss progression in experimentally induced periodontitis. Fort...
Comparative therapeutic use of Risedronate and Calcarea phosphorica-allopathy versus homeopathy-in bone repair in castrated rats
Allopathy Homeopathy Calcarea phosphorica Fracture healing
2009/10/19
Osteoporosis, a disease characterized by progressive bone loss, has been the target of several studies in the past few years. It results in a much higher risk for fractures and might cause slower bone...
The influence of ovariectomy,simvastatin and sodium alendronate on alveolar bone in rats
Alendronate Models animal Osteoporosis Ovariectomy Simvastatin
2009/10/19
Bisphosphonates are currently used in the treatment of many diseases involving increased bone resorption such as osteoporosis. Statins have been widely used for the treatment of hypercholesterolemia a...
Comparison of histometric and morphometric analyses of bone height in ligature-induced periodontitis in rats
Histology Alveolar bone loss Periodontium
2009/10/19
The purpose of this study was to compare histologic and morphometric procedures of bone height measurement. Microscopic measurements are the most frequent methods in periodontal studies with animals, ...