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Is the randomized clinical trial the gold standard of research?
randomized clinical trial gold standard of research
2008/12/29
All research has flaws. Some flaws are so trivial that the research can still stand as the definitive study. Other flaws prevent a study from being definitive, but the study still provides useful gu...
Between the wars on terror and in Iraq, the ubiquitous presidential politics, and the celebrity trials, little else has recently engendered notable television or print news attention. One such unfortu...
Quality Control of Laboratory Methods for Semen Evaluation in a Multicenter Research Study
Sperm concentration semem volume sperm motility quality control observer variation precision
2008/12/22
Rigorously standardized laboratory protocols and strict quality control (QC) are essential for meaningful comparisons between semen quality data from multiple sites. We describe our experience wit...
Standardized Methods for Semen Evaluation in a Multicenter Research Study
Sperm concentration semen volume sperm motility quality control observer variation precision
2008/12/22
Semen evaluation methodology is complex and difficult to standardize. Rigorously standardized laboratory protocols and strict quality control (QC) are essential for meaningful comparison of data fro...
Oxidative Stress and Male Infertility: From Research Bench to Clinical Practice
Oxidative Stress Male Infertility Research Bench to Clinical Practice
2008/12/15
Extensive research in our center at the Cleveland Clinic indicates that the seminal oxidative stress test has diagnostic and prognostic capabilities beyond those of conventional tests of sperm quality...